The effect of a gram-negative bacterial endotoxin and cloprostenol on the plasma levels of 15-keto-13,14-dihydro-PGF2α, progesterone, oestradiol-17β, oestrone sulphate and luteinizing hormone in non-pregnant and 60-day-pregnant gilts

Cort, N.; Kindahl, H.; Einarsson, S.

doi:10.1016/0378-4320(86)90026-6

Cited by 27 publications

(35 citation statements)

References 35 publications

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“…Earlier studies (Cort et al. 1986) in pregnant and nonpregnant gilts have demonstrated that progesterone decreased following LPS owing to luteolysis and subsequent abortions.…”

Section: Discussionmentioning

confidence: 95%

“…It has earlier been demonstrated that LPS stimulates the synthesis and release of prostaglandin in several species (Fredriksson et al. 1985; van Miert 1985; Cort et al. 1986).…”

Section: Discussionmentioning

confidence: 99%

“…The outer cell membranes of these Gram‐negative bacteria are composed of lipopolysaccarides (endotoxins) and have been shown to stimulate prostaglandin synthesis and release in cattle (van Miert 1985), goats (Fredriksson et al. 1985) and pigs (Cort et al. 1986).…”

Section: Introductionmentioning

confidence: 99%

“…1986). Furthermore, Cort et al. (1986) have demonstrated that lipopolysaccharide (LPS) of Salmonella typhimurium causes luteolysis and abortion in pregnant gilts.…”

Section: Introductionmentioning

confidence: 99%

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Postovulatory Effect of Intravenous Administration of Lipopolysaccharide (Escherichia coli, O55:B5) on the Endocrine Status of Recently Ovulated Sows

Mwanza¹,

Madej²,

Kindahl³

et al. 2001

Reprod Domest Anim

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The effects of lipopolysaccharide (Escherichia coli, O55:B5), administered 18 h after ovulation in the second oestrus after weaning on the hormonal profiles in 14 Swedish cross-bred (Landrace x Yorkshire) multiparous sows were studied. The endotoxin group (E-group) sows were administered with 300 ng/kg of lipopolysaccharide (LPS) whereas the control group (C-group) sows were administered 5 ml of saline intravenously via an indwelling jugular cannula. Blood samples for hormonal analyses were collected from all sows until slaughter. In the E-group, progesterone, cortisol and prostaglandin F(2 alpha) metabolite levels increased significantly (p < 0.05) following LPS compared with the C-group. It can be concluded from this study that apart from elevating cortisol and prostaglandin F(2 alpha) metabolite, LPS also elevates progesterone levels.

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“…Earlier studies (Cort et al. 1986) in pregnant and nonpregnant gilts have demonstrated that progesterone decreased following LPS owing to luteolysis and subsequent abortions.…”

Section: Discussionmentioning

confidence: 95%

“…It has earlier been demonstrated that LPS stimulates the synthesis and release of prostaglandin in several species (Fredriksson et al. 1985; van Miert 1985; Cort et al. 1986).…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…1986). Furthermore, Cort et al. (1986) have demonstrated that lipopolysaccharide (LPS) of Salmonella typhimurium causes luteolysis and abortion in pregnant gilts.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Postovulatory Effect of Intravenous Administration of Lipopolysaccharide (Escherichia coli, O55:B5) on the Endocrine Status of Recently Ovulated Sows

Mwanza¹,

Madej²,

Kindahl³

et al. 2001

Reprod Domest Anim

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“…The number of circulating neutrophils and plasma concentrations of cortisol and 15‐ketodihydro‐PGF 2α have in other studies been shown to be useful indicators of inflammation in pigs (Cort et al., 1986; Magnusson et al., 1994; Garcia et al., 1998). However, it is also well established that these parameters vary considerably around parturition (Baldwin and Stabenfeldt, 1975; Magnusson and Fossum, 1992; Österlundh et al., 1998).…”

Section: Discussionmentioning

confidence: 98%

Sows Intramammarily Inoculated withEscherichia coli: Influence of Time of Infection, Hormone Concentrations and Leucocyte Numbers on Development of Disease

Magnusson

Mörner

Persson

et al. 2001

Journal of Veterinary Medicine, Series B

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The aim of this study was to identify factors that in¯uence the development of disease in sows inoculated with Escherichia coli in the mammary gland. Ten cross-bred primiparous sows were intramammarily inoculated with living E. coli bacteria at different time points before parturition: seven sows within 48 h before parturition and three sows approximately 96 h before parturition. Before and after inoculation, blood samples and mammary gland biopsy specimens were collected and clinical observations were made. All seven sows inoculated close to parturition developed a rectal temperature of >39.5°C during the ®rst 48 h post-partum and two of them also showed other signs of clinical disease. In the sows inoculated 4 days before parturition, the rectal temperature never exceeded 39.5°C during the ®rst 48 h post-partum and none of them showed any other sign of clinical disease. There was a tendency (P < 0.1) that histological signs of mastitis were more frequent in the sows inoculated close to parturition. There were no overall differences between the two groups of sows in plasma concentrations of cortisol, oestradiol-17b and 15-ketodihydro-PGF 2a before inoculation. Before inoculation, the number of neutrophils in the blood was overall higher (P < 0.05) in the group of sows that were inoculated close to parturition. In comparison, the number of lymphocytes before inoculation had a tendency (P < 0.1) to be lower in that group. The data suggest that the time of infection of the mammary gland relative to parturition and the number of circulating neutrophils at the time of infection in¯uence the development of clinical coliform mastitis in the sow.

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A clinical study on the effect of a gram-negative bacterial endotoxin and cloprostenol in non-pregnant and 60-day-pregnant gilts

Cort

1986

Animal Reproduction Science

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The effect of a gram-negative bacterial endotoxin and cloprostenol on the plasma levels of 15-keto-13,14-dihydro-PGF2α, progesterone, oestradiol-17β, oestrone sulphate and luteinizing hormone in non-pregnant and 60-day-pregnant gilts

Cited by 27 publications

References 35 publications

Postovulatory Effect of Intravenous Administration of Lipopolysaccharide (Escherichia coli, O55:B5) on the Endocrine Status of Recently Ovulated Sows

Postovulatory Effect of Intravenous Administration of Lipopolysaccharide (Escherichia coli, O55:B5) on the Endocrine Status of Recently Ovulated Sows

Sows Intramammarily Inoculated withEscherichia coli: Influence of Time of Infection, Hormone Concentrations and Leucocyte Numbers on Development of Disease

A clinical study on the effect of a gram-negative bacterial endotoxin and cloprostenol in non-pregnant and 60-day-pregnant gilts

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