The dynamics of the coronary venous pressure in the dog

Tiedt, N; Litwin, J; Skolasińska, K

doi:10.1007/bf00412533

Cited by 12 publications

(6 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The pressure wave in each cardiac cycle had two peaks, which corresponded to the 'a' and 'v' waves of Tiedt, Litwin & Skolakinska (1966). The 'v' wave was maximal about 90 msec after the QRS complex.…”

Section: Resultsmentioning

confidence: 99%

“…Resting coronary venous pressure With the Morawitz cannula in place in the mouth of the coronary sinus, and with free flow of venous blood through it, the recorded coronary venous pressure wave was small in amplitude, and the pressures were never more than 10-15 mm Hg systolic and 05 mm Hg diastolic. The pressure wave in each cardiac cycle had two peaks, which corresponded to the 'a' and 'v' waves of Tiedt, Litwin & Skolakinska (1966). The 'v' wave was maximal about 90 msec after the QRS complex.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

The reflex cardiovascular depression caused by occlusion of the coronary sinus in the dog

Muers¹,

Sleight²

1972

The Journal of Physiology

View full text Add to dashboard Cite

4. During occlusions, there was inhibition of activity in single and small multi-fibre preparations of sympathetic efferent nerves in the ansae subclaviae and the cervical sympathetic.5. On the right side, nearly all afferent fibres ran in the recurrent cardiac nerve. There was no concentration of afferents in one cardiac nerve on the left side.6. It was concluded that the cardiovascular depression was reflex, and was caused by the stimulation of nerves or nerve endings in the ventricles of the heart.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

The reflex cardiovascular depression caused by occlusion of the coronary sinus in the dog

Muers¹,

Sleight²

1972

The Journal of Physiology

View full text Add to dashboard Cite

show abstract

“…They ranged from 16-20 mm in animals of 10-16-5 kg. 362 Coronary Sinus Distension 363 Coronary venous pressure The amplitude of the pressure waves recorded via the cannula, with its terminal balloon deflated, were similar to those recorded by Tiedt et al [1966] who used an indwelling catheter (2 mm o. d.) without through flow, and were typically less than 10-15 mm Hg systolic and less than 0.5 mm Hg diastolic. There was therefore no outflow obstruction when the cannulae were in place.…”

Section: Resultsmentioning

confidence: 57%

“…They ranged from 16-20 mm in animals of 10-16-5 kg. Tiedt et al [1966] who used an indwelling catheter (2 mm o. d.) without through flow, and were typically less than 10-15 mm Hg systolic and less than 0.5 mm Hg diastolic. There was therefore no outflow obstruction when the cannulae were in place.…”

Section: Resultsmentioning

confidence: 99%

The Cardiovascular Effects of Coronary Sinus Distension in the Anaesthetised Dog

Muers¹,

Sleight²

1972

Exp Physiol

View full text Add to dashboard Cite

Experiments were carried out to determine whether the systemic hypotension caused by distension of the coronary sinus is reflex in origin. In anaesthetized open-chest dogs, indwelling Morawitz balloon cannulae were used to distend the sinus. Eighty-three distensions in fourteen experiments with intact vagi caused systemic hypotension and tachyeardia, but there was no significant change in this response in a further twenty-two tests after the cervical vagi had been cut, or cooled (to less than 5°C). Recordings were made of sympathetic efferent nerve activity in few-fibre preparations from the ventral ansae subelaviae. Activity was reduced during the hypotension reflexly caused by intrapericardial nicotine but was increased after coronary sinus distension. The increase in activity occurred both with intact and sectioned vagi. It was concluded that the excitation of cardiac mechanoreceptors in the coronary sinus wall by distension does not produce measurable reflex depression of the circulation, and that the hypotension observed after sinus distension is mechanically caused, rather than reflex in origin as earlier studies have implied.For many years there has been histological evidence of a rich afferent innervation of the heart, and there have been numerous reports of cardiovascular reflex effects from the heart [Heymans and Neil, 1958;Sleight, 1971].Szentivanyi and Juhasz-Nagy [1960, 1962] reported that distension without obstruction of the coronary sinus of the anaesthetised dog by an indwelling Morawitz balloon cannula [Morawitz and Zahn, 1914] produced systemic arterial hypotension. This hypotension was abolished by bilateral cervical vagotomy, selective cardiac denervation, or the application of cocaine to the outside of the sinus; heart rate was not measured. The average fall in blood pressure reported was about 20 mm Hg with a range of 10-70 mm Hg from resting mean blood pressure levels of about 55-140 mm Hg. The pressure in the distending balloon was between 10-40 mm Hg and the hypotension produced persisted as long as the balloon remained inflated, with only a small, slow rise towards the previous level. Hypotension was maintained for as long as 2 hr in one experiment. This pattern is very different from that caused by maintained distension of an isolated carotid sinus with intact vagi, when the arterial blood pressure returns to a near normal value within a few minutes [Scher and Young, 1963;Gillam, 1968].Szentivanyi and Juhasz-Nagy cited three pieces of evidence to support the conclusion that the response was reflex. First, the response could not be obtained after bilateral vagotomy, but was present after atropine: second, it was abolished by applying cocaine to the 'environment' of the sinus; and third,

show abstract

“…Dissection may disturb the parasympathetic fibres to the coronary vessels, whilst cannulation can influence the coronary outflow resistance and venous pressure (26) and thereby coronary perfusion pressure. Myocardial metabolism.…”

Section: Discussionmentioning

confidence: 99%

Vagal control of coronary blood flow in dogs

Tiedt

Religa

1979

Basic Res Cardiol

Self Cite

View full text Add to dashboard Cite

The experiments were performed on open-chest mongrel dogs, the hearts being paced at a constant rate. Both vagi were cut in the neck and the peripheral ends were stimulated with frequencies of 1, 5, 10, 15, 20, 25, 30, 35, 40 and 50 cycles per sec (30 sec, 8 V, 2 msec). Adrenergic beta-receptors were blocked with propranolol and adrenergic alpha-receptors with dihydroergotamine. Coronary flow was measured with electromagnetic flowmeters on the descending branch of the left coronary artery. A significant increase in coronary flow was observed with rising frequency of stimulation. This increase was 15 percent with 30 Hz and decreased with higher frequencies. The total coronary resistance reached its lowest level at the frequency of 30 cycles per sec. The results clearly indicate the parasympathetic control of myocardial blood flow.

show abstract

The dynamics of the coronary venous pressure in the dog

Cited by 12 publications

References 16 publications

The reflex cardiovascular depression caused by occlusion of the coronary sinus in the dog

The reflex cardiovascular depression caused by occlusion of the coronary sinus in the dog

The Cardiovascular Effects of Coronary Sinus Distension in the Anaesthetised Dog

Vagal control of coronary blood flow in dogs

Contact Info

Product

Resources

About