Abstract:Experiments were carried out to determine whether the systemic hypotension caused by distension of the coronary sinus is reflex in origin. In anaesthetized open-chest dogs, indwelling Morawitz balloon cannulae were used to distend the sinus. Eighty-three distensions in fourteen experiments with intact vagi caused systemic hypotension and tachyeardia, but there was no significant change in this response in a further twenty-two tests after the cervical vagi had been cut, or cooled (to less than 5°C). Recordings … Show more
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