The Dual Relationship Between Thymectomy and Autoimmunity

Sherer, Yaniv; Bar‐Dayan, Yaron; Shoenfeld, Yehuda

doi:10.1007/978-1-4612-1610-0_23

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2001

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“…However, the mice that developed the SLE-like illness showed a significantly lower incidence of type I diabetes and amelioration of the pancreatic insulitis. This study's results are an example of the 'kaleidoscope phenomenon' [26][27][28][29][30] and they point to the importance of immune dysregulation in shift from one autoimmune disease to another-especially in individuals genetically prone to develop autoimmune conditions. One hypothesis offered to explain this manifestation is the 'common gene hypothesis'.…”

Section: Discussionmentioning

confidence: 91%