The Dual Antimelanogenic and Antioxidant Activities of the Essential Oil Extracted from the Leaves of<i>Acorus macrospadiceus</i>(Yamamoto) F. N. Wei et Y. K. Li

Huang, Huey-Chun; Wang, Hsiao-Fen; Yih, Kuang-Hway; Chang, Long-Zen; Chang, Tsong-Min

doi:10.1155/2012/781280

Cited by 18 publications

(18 citation statements)

References 28 publications

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“…Further, we have screened over thirty types of plants and evaluated the potential dermatological effects of the essential oils extracted from these plants, and found the essential oils isolated from the leaves of Vitex negundo Linn and Acorus macrospadiceus (Yamamoto, F. N. Wei, Y. K. Li et al .) exhibit antioxidant activities and antimelanogenic properties [34,56]. Therefore, the chemical constituents found in Artemisia argyi leaves may play major roles in the biological activities and pharmacological properties, but the biological roles of the chemicals in both essential oils still remained to be elucidated in the near future.…”

Section: Resultsmentioning

confidence: 99%

Dual Bioactivities of Essential Oil Extracted from the Leaves of Artemisia argyi as an Antimelanogenic versus Antioxidant Agent and Chemical Composition Analysis by GC/MS

Huang

Wang

Yih

et al. 2012

IJMS

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The study was aimed at investigating the antimelanogenic and antioxidant properties of essential oil when extracted from the leaves of Artemisia argyi, then analyzing the chemical composition of the essential oil. The inhibitory effect of the essential oil on melanogenesis was evaluated by a mushroom tyrosinase activity assay and B16F10 melanoma cell model. The antioxidant capacity of the essential oil was assayed by spectrophotometric analysis, and the volatile chemical composition of the essential oil was analyzed with gas chromatography-mass spectrometry (GC/MS). The results revealed that the essential oil significantly inhibits mushroom tyrosinase activity (IC50 = 19.16 mg/mL), down-regulates B16F10 intracellular tyrosinase activity and decreases the amount of melanin content in a dose-dependent pattern. Furthermore, the essential oil significantly scavenged 2,2-diphenyl-1-picryl-hydrazyl (DPPH) and 2,2′-azino-bis (3-ethylbenzthiazoline- 6-sulphonic acid) ABTS radicals, showed an apparent reduction power as compared with metal-ion chelating activities. The chemicals constituents in the essential oil are ether (23.66%), alcohols (16.72%), sesquiterpenes (15.21%), esters (11.78%), monoterpenes (11.63%), ketones (6.09%), aromatic compounds (5.01%), and account for a 90.10% analysis of its chemical composition. It is predicted that eucalyptol and the other constituents, except for alcohols, in the essential oil may contribute to its antioxidant activities. The results indicated that essential oil extracted from A. argyi leaves decreased melanin production in B16F10 cells and showed potent antioxidant activity. The essential oil can thereby be applied as an inhibitor of melanogenesis and could also act as a natural antioxidant in skin care products.

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Section: Resultsmentioning

confidence: 99%

Dual Bioactivities of Essential Oil Extracted from the Leaves of Artemisia argyi as an Antimelanogenic versus Antioxidant Agent and Chemical Composition Analysis by GC/MS

Huang

Wang

Yih

et al. 2012

IJMS

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“…It has been demonstrated that some phenolic components of EOs are oxidized by contact with reactive oxygen species (ROS) producing very reactive phenoxyl radicals. These types of radical reactions are enhanced by the presence of transition metal ions, such as Fe 2+ , Cu 2+ , Zn 2+ , Mg 2+ , or Mn 2+ [44,45,46]. In this regard, some studies have shown higher oxidative stability of ethanolic EOs.…”

Section: Influence Of Eos Production On Their Chemical Compositionmentioning

confidence: 99%

Essential Oils as a Feed Additives: Pharmacokinetics and Potential Toxicity in Monogastric Animals

Horký

Skaličková

Šmerková

et al. 2019

Animals

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Essential oils (EOs) are now a hot topic in finding modern substitutes for antibiotics. Many studies have shown positive results and confirmed their high antibacterial activity both in vitro and in vivo. Deservedly, there is an attempt to use EOs as a substitute for antibiotics, which are currently limited by legislation in animal breeding. Given the potential of EOs, studies on their fate in the body need to be summarized. The content of EO’s active substances varies depending on growing conditions and consequently on processing and storage. Their content also changes dynamically during the passage through the gastrointestinal tract and their effective concentration can be noticeably diluted at their place of action (small intestine and colon). Based on the solubility of the individual EO’s active substances, they are eliminated from the body at different rates. Despite a strong antimicrobial effect, some oils can be toxic to the body and cause damage to the liver, kidneys, or gastrointestinal tissues. Reproductive toxicity has been reported for Origanum vulgare and Mentha arvensis. Several publications also address the effect on the genome. It has been observed that EOs can show both genoprotective effects (Syzygium aromaticum) and genotoxicity, as is the case of Cinnamomum camphor. This review shows that although oils are mainly studied as promising antimicrobials, it is also important to assess animal safety.

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“…In recent years, the medicinal values of Acorus were increasingly recognized, and more Acorus materials had been collected for medications ( Huang et al, 2012 ; Shu et al, 2018a ). Unfortunately, the authorized taxonomic treatment of Acorus species confused collectors and consumers with their classification, partly because of their similar morphology, especially when dried.…”

Section: Introductionmentioning

confidence: 99%

From Folk Taxonomy to Species Confirmation of Acorus (Acoraceae): Evidences Based on Phylogenetic and Metabolomic Analyses

et al. 2020

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Plants in Acorus have been used as herbal medicine by various linguistic groups for thousands of years. Arguments of taxonomy of Acorus among scientists resulted in confusions and misuses of Acorus plants. The present study used different methods to investigate the classification of the genus, based on folk taxonomy. The relationships among Acorus species were revealed through phylogenetic analyses by constructing the Maximum Likelihood and Bayesian phylogenetic analyses based on sequences of two chloroplast regions (trnL-trnF and rbcL). All samples named with two so-called synonyms, Acorus macrospadiceus (Yamam.) F. N. Wei and Y. K. Li and Acorus tatarinowii Schott collected from different habitats, were clustered into separate groups, which revealed that they represented two independent species. Multivariate statistical analysis of metabolites from different Acorus populations were carried out based on UPLC-QTOF-MS data. Three independent analysis, principal component analysis, heat-map analysis, and hierarchical cluster analysis, showed that A. macrospadiceus and A. tatarinowii are different from two recognized species in the genus, A. calamus L. and A. gramineus Aiton. The results of phylogenetics and chemotaxonomy, together with morphological and ecological evidences, were consistent with traditional knowledge of local people related to Acorus taxa, which proved the significance of parataxonomy. Multiple evidences including morphological, ecological, folk taxonomic, phylogenetic, and chemical taxonomic results suggested that there are four species in the genus Acorus.

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The Dual Antimelanogenic and Antioxidant Activities of the Essential Oil Extracted from the Leaves ofAcorus macrospadiceus(Yamamoto) F. N. Wei et Y. K. Li

Cited by 18 publications

References 28 publications

Dual Bioactivities of Essential Oil Extracted from the Leaves of Artemisia argyi as an Antimelanogenic versus Antioxidant Agent and Chemical Composition Analysis by GC/MS

Dual Bioactivities of Essential Oil Extracted from the Leaves of Artemisia argyi as an Antimelanogenic versus Antioxidant Agent and Chemical Composition Analysis by GC/MS

Essential Oils as a Feed Additives: Pharmacokinetics and Potential Toxicity in Monogastric Animals

From Folk Taxonomy to Species Confirmation of Acorus (Acoraceae): Evidences Based on Phylogenetic and Metabolomic Analyses

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