The drug aspects of the white sapotes

Morton, Julia F.

doi:10.1007/bf02860187

Cited by 8 publications

(1 citation statement)

References 15 publications

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“…C. edulis fruits are used in gastronomy and serve as an addition to salads and ice creams. Aside from being utilized as food, the leaves and seeds are used in infusions as sedative agents [12][13][14] and painkillers for rheumatism and arthritis [15][16][17]. Furthermore, folk-medicinal reports have mentioned treating diarrhea in children by burning the leaves.…”

Section: Natural Occurrence Of Zapotinmentioning

confidence: 99%

Zapotin, a Polymethoxyflavone, with Potential Therapeutic Attributes

Strawa

Jakimiuk

2021

IJMS

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The use of plants as traditional medicines is common and has prevailed in many different cultures over time. Polymethoxyflavones (PMFs) are natural polyphenols from the group of flavonoids. Zapotin, a member of the PMFs, is found mainly in citrus plants and is almost exclusively limited to their peels. The chemical structure of zapotin has been questioned from the very beginning, since the structure of flavonoids with a single oxygen atom in the C2′ position is extremely rare in the plant kingdom. To clarify this, the structural determination and bio-inspired synthesis of zapotin are discussed in detail in this review. Due to the broad biological potential of PMFs, the complication in the isolation process and characterization of PMFs, as well as their purification, have been estimated by adapting various chromatographic methods. According to available data from the literature, zapotin may be a promising curative agent with extensive biological activities, especially as a chemopreventive factor. Apart from that, zapotin acts as an antidepressant-like, anticancer, antifungal, and antioxidant agent. Finally, accessible studies about zapotin metabolism (absorption, distribution, metabolism, excretion, and toxicity) underline its potential in use as a therapeutic substance.

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