The distribution over time of costs and social net benefits for pertussis immunization programs

Girard, Dorota Zdanowska

doi:10.1007/s10754-009-9058-2

Cited by 7 publications

(3 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 . The vaccine with the highest number of studies was Influenza/H1N1 with 32%, followed by Dengue with 8% (Agusto and Khan , 2018 ; Rodrigues et al , 2014 ), and HPV (Demarteau et al , 2012 ), Measles (Thakkar et al , 2019 ), Pertussis (Girard , 2010 ), and Polio (Tebbens et al , 2010 ) were each considered in 4% of studies. Addressing vaccines and other products (including antidotes, vital vaccines, medicines to treat HIV/AIDS, malaria, tuberculosis, among others) occurred in 12% of papers, and 4% of studies addressed multiple vaccines (Engineer et al , 2009 ).…”

Section: Resultsmentioning

confidence: 99%

“…Different experiments are presented to show the different optimal ordering policies for different shelf lives of critical perishable goods. The outputs of the model are the actions that must be executed at each decision period, as a function of the inventory level at the onset of the current decision period Girard ( 2010 ) This paper performs a cost analysis that compares the total costs and benefits among different immunaztion programs with varying percentages of vaccination coverage. Data from England and Wales is used.…”

Section: Appendix Amentioning

confidence: 99%

See 1 more Smart Citation

Optimization methods for large-scale vaccine supply chains: a rapid review

et al. 2022

View full text Add to dashboard Cite

Global vaccine revenues are projected at $59.2 billion, yet large-scale vaccine distribution remains challenging for many diseases in countries around the world. Poor management of the vaccine supply chain can lead to a disease outbreak, or at worst, a pandemic. Fortunately, a large number of those challenges, such as decision-making for optimal allocation of resources, vaccination strategy, inventory management, among others, can be improved through optimization approaches. This work aims to understand how optimization has been applied to vaccine supply chain and logistics. To achieve this, we conducted a rapid review and searched for peer-reviewed journal articles, published between 2009 and March 2020, in four scientific databases. The search resulted in 345 articles, of which 25 unique studies met our inclusion criteria. Our analysis focused on the identification of article characteristics such as research objectives, vaccine supply chain stage addressed, the optimization method used, whether outbreak scenarios were considered, among others. Approximately 64% of the studies dealt with vaccination strategy, and the remainder dealt with logistics and inventory management. Only one addressed market competition (4%). There were 14 different types of optimization methods used, but control theory, linear programming, mathematical model and mixed integer programming were the most common (12% each). Uncertainties were considered in the models of 44% of the studies. One resulting observation was the lack of studies using optimization for vaccine inventory management and logistics. The results provide an understanding of how optimization models have been used to address challenges in large-scale vaccine supply chains.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Appendix Amentioning

confidence: 99%

Optimization methods for large-scale vaccine supply chains: a rapid review

et al. 2022

View full text Add to dashboard Cite

show abstract

“…However, this result is to be counterbalanced by an underestimation of vaccination cost obtained in the analysis when the response time identified by the transfer function models for pertussis and measles is not considered. In fact, the assumption of a delayed period of two and three years is to generate more expensive transformations in total cost compared to those where there is an instantaneous reaction of morbidity and mortality to the changes in vaccination rate [32]. This ensues from the definition that the total cost of vaccination program combines the cost of vaccine provision with cost of treating cases.…”

Section: Discussionmentioning

confidence: 99%

A Comparative Economic Analysis of Immunization Programs for Pertussis and Measles: The Use of ARIMA Model to Study the Epidemiological Situation in England and Wales

Girard¹

2013

Int. J. Stats. Med. Res.

View full text Add to dashboard Cite

Objective: We evaluate pertussis and measles immunization strategies and compare the consequences in terms of health effects and economic costs.Methods: Based on epidemiological data for pertussis and measles in England and Wales from 1970 to 2012, we use ARIMA approach to model the relation between notification cases and vaccination coverage for each disease. We then perform an economic evaluation of vaccination programs at 95% and discuss the benefits for the society to achieve this level when compared with lower vaccination rates currently observed. The advantages for the society of increasing vaccination coverage up to 98% are considered respectively for pertussis and measles.Results: The programs at a 95% vaccination rate, which is able to significantly reduce the mortality and the morbidity due to pertussis and measles, are confirmed to be the best cost saving immunization strategy. The total social net benefits are systematically maximized when the programs are compared to strategies with lower vaccination coverage. The decision to exceed the herd immunity level and reach the rate at 98% is economically justified for measles, while for pertussis the programs at 98% are less cost effective than the programs at 95%. Conclusion:Additional efforts must be carried out to promote measles vaccination since immunization strategies at 95% and at higher rates are recommended on epidemiological and economic grounds.

show abstract

Skilled migration and health outcomes in developing countries

Uprety

2018

Int J Health Econ Manag.

View full text Add to dashboard Cite

Many studies have found that health outcomes decline when health professionals leave the country, but do such results remain consistent in gender- and income-disaggregated skilled migration? To help uncover explanations for such a pro-migration nature of health outcomes, the present study revisits this topic but allows for associations of skilled migration with mortality and life expectancy to differ between male and female, and between low- and high-income countries. Using a panel of 133 developing countries as source and 20 OECD countries as destination from 1980 to 2010 allowing the coefficient on emigration across different education levels to differ, the study finds the negative effect of high-skilled emigration on health outcomes. Such effect is more pronounced for high-skilled female migration than those for male and for low-income countries than for middle-and high-income countries. Results also show that such adverse effect is larger for African countries than non-African ones. However, the low-skilled migration appears to be insignificant to affect health outcomes in developing countries. Thus, skilled migration is detrimental to longevity in developing countries but unskilled migration is not.

show abstract

The distribution over time of costs and social net benefits for pertussis immunization programs

Cited by 7 publications

References 39 publications

Optimization methods for large-scale vaccine supply chains: a rapid review

Optimization methods for large-scale vaccine supply chains: a rapid review

A Comparative Economic Analysis of Immunization Programs for Pertussis and Measles: The Use of ARIMA Model to Study the Epidemiological Situation in England and Wales

Skilled migration and health outcomes in developing countries

Contact Info

Product

Resources

About