The 'distal-dorsal difference': a thermographic parameter by which to differentiate between primary and secondary Raynaud's phenomenon

Abstract

Parameters derived from thermography (incorporating both a heat and cold challenge) aid in the prediction of SSc in patients with RP.

Thermal Disparity between Fingers after Cold-water Immersion of Hands: A Useful Indicator of Disturbed Peripheral Circulation in Raynaud Phenomenon Patients

“…Several studies have reported that thermographic examinations are useful for differentiating secondary RP, such as systemic sclerosis, from primary RP (9,(13)(14)(15)(16)(17). In our study, the RP patients with systemic sclerosis had a significantly lower recovery rate and DDD and a significantly higher temperature disparity than the other patients with RP.…”

Efficacy and safety of Korean red ginseng for cold hypersensitivity in the hands and feet: A randomized, double-blind, placebo-controlled trial

“…It has been used to evaluate the severity of vasoconstriction (Clark et al, 1999;Pauling et al, 2011). DDD of 41 1C in any finger at room temperature is considered a specific indicator of vascular disease (Anderson et al, 2007). Calculating the maximum DDD across all digits and the number of fingers with DDD 41 1C appeared to provide a greater discriminatory capacity than any other analysis that had been adopted in previous studies investigating DDD (Pauling et al, 2011).…”

“…DDD is the difference in temperature between a finger and the dorsum of the hand (Anderson et al, 2007). It has a positive value if the finger is colder than the dorsum, and a high DDD indicates severe cold hypersensitivity in the fingers.…”

Chronic cerebral ischemia associated with Raynaud's syndrome

“…Дисфункция эндотелия -патологическое состояние, возникающее в результате нарушения регионального кровообращения и микроцир-куляции, приводящее к усиленным тромбообразованию и адгезии лейкоцитов. Наибольшее значение имеет продук-ция оксида азота, эндотелина-1, серотонина, тромбокса-на и ангиотензина, уровень которых у больных с СР повы-шается под воздействием холода [10]. Регуляция сосуди-стого тонуса также вплотную связана с нейропептидами (связанный с геном кальцитонина пептид, нейропептид Y) и агентами, взаимодействующими с α-адренорецеп-торами, что дополнительно усиливает вазоконстрикцию.…”