The term comorbidity, a concurrent damage to two or more organs or systems, is widely discussed in the literature. In elderly patients, any somatic illness is comorbid to cerebrovascular diseases that hampers early diagnosis and treatment of the latter. Due to the complicity and multicomponent structure of the pathogenesis of comorbidity, many drugs should be used to treat different patterns of the pathological process that results in polypragmasia often accompanied by complications. Therefore, a search for new ways in the treatment of these patients is still urgent.