The diagnostic value of combining conventional, diffusion-weighted imaging and dynamic contrast-enhanced MRI for salivary gland tumors

Abstract

An evaluation combining MRI morphologic findings and functional MRI (ADCs and TIC) appears to be useful in differentiating benign from malignant tumors in salivary gland tumors. Advances in knowledge: The study firstly dealt with the combination of conventional MRI, DWI-MRI with DCE-MRI in salivary gland tumors.

RETRACTED ARTICLE: The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors

“…Analysis of TIC had high sensitivity and specificity in differentiating benign from malignant parotid gland tumors. Pleomorphic adenoma could be easily Zheng et al [7] evaluated salivary gland tumors based on the TIC classification by Yabuuchi et al [6] and found that most cases of pleomorphic adenomas (88.9%) had type A TIC; all cases of Warthin's tumor had type B TIC; regarding malignant parotid gland tumors, most of them (81.8%) had type C TIC, and only 18.2% had type B TIC. Lam et al [8] also studied TIC in differentiation between benign and malignant parotid gland tumors and found that 96.2% of pleomorphic adenomas had type A TIC; type C TIC was observed in all cases of malignant parotid gland tumors except lymphoma.…”

“…Regarding WR values of Warthin's tumor and malignant parotid gland tumor, Zheng et al [7] stated that WR of Warthin's tumor (57.5 ± 8.1%) was significantly higher than that of malignant parotid gland tumors (17.2 ± 13.2%). Gokce [5] performed analysis of several previous studies in literature and concluded that WR value of Warthin's tumor was significantly higher than that of malignant parotid gland tumors.…”

“…This is in agreement with Celebi et al [16] who stated that cut off mean ADC value of 1.315 × 10 −3 mm 2 /s could [11] stated that cut off mean ADC value of 1.267 × 10 −3 mm 2 /s could differentiate pleomorphic adenoma from malignant parotid gland tumor with 95.8% sensitivity and 93% specificity. Zheng et al [7] found that mean ADC value of 1.29 × 10 −3 mm 2 /s had 100% sensitivity and 91.7% specificity in differentiating pleomorphic adenoma from malignant parotid gland tumor. Several previous studies [7,[10][11][12][14][15][16][17][18] found that there was no significant difference between the mean ADC value of Warthin's tumor (mean ADC value ranged from 0.74 to 0.99 × 10 −3 mm 2 /s) and malignant parotid gland tumors (mean ADC value ranged from 0.795 to 1.21 × 10 −3 mm 2 /s).…”

Diffusion‐weighted magnetic resonance imaging in the palatal tumors: Usefulness of apparent diffusion coefficient value for characterization of benign and malignant tumors

“…Regarding the ADC values of salivary gland tumors, Terra et al 10 showed that the mean ADC values for pleomorphic adenoma was 1.91 × 10 −3 mm 2 s −1 . Zeng et al 17 showed that the mean ADC values for the different mass types were as follows: 1.72 × 10 −3 mm 2 s −1 for pleomorphic adenomas, 0.74 × 10 −3 mm 2 s −1 for adenolymphoma, and 0.95 × 10 −3 mm 2 s −1 for malignant tumors. In this study, ADC values of minor salivary gland tumors were adenoid cystic carcinoma: 0.86 × 10 −3 mm 2 s −1 , pleomorphic adenoma: 1.49 × 10 −3 mm 2 s −1 , and myoepithelioma: 1.71 × 10 −3 mm 2 s −1 .…”

Benigne Neoplasien der Orbita

“…Eine Studie von Aghaghazvini et al zeigte, dass mittels DCE-Sequenz eine Differenzierung der Tumorentität bei Speicheldrüsentumoren vereinfacht werden kann[17]. Auch die Studie von Zheng et al demonstrierte, dass die DWI-wie auch die DCE-Sequenz nützliche Informationen bezüglich der Einordnung von Tumoren der Speicheldrüse liefert[18]. Ähnliche Ergebnisse liefern auch andere Studien, die die Effektivität der DWI-bzw.…”