The development of the human hyoid–larynx complex revisited

Bakker, Bernadette S. de; Bakker, Henri M. de; Soerdjbalie‐Maikoe, Vidija; Dikkers, Frederik G.

doi:10.1002/lary.26987

Cited by 26 publications

(31 citation statements)

References 28 publications

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“…Connection of the lesser horn with the body and the junction between the body and the greater horn are formed by a dense stripe of closely packed cells (fetuses 85,0 mm of PCL). The prenatal morphogenesis of HB is always connected with transformation of the branchial arches (de Bakker et al, 2018(de Bakker et al, : 1830. The origin of the greater horns is considered to be of the lateral cartilages of the third visceral arch, the lesser horn originates from the distal part of Reichert's cartilage (Kadir et al, 2015: 45).…”

Section: Discussionmentioning

confidence: 99%

Spatio-Temporal Morphological Changes of Structures in Infrahyoid Triangles in Human Fetuses During Fetal Period of Human Ontogenesis

2020

European Journal of Medicine

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Infrahyoid triangles in anterior region of neck contain crucial structures for human body like trachea, thyroid gland, nerve plexuses and magistral blood vessels. Infrahyoid muscle flaps are often used for reconstructive surgeries that is why the topography of their innervation is important for successful dissection and minimization of postsurgical complications. That is why the aim of our study was to examine topographical peculiarities of structures in infrahyoid triangles in human fetuses during late intrauterine prenatal development (PND) that would provide clinical practitioners like pediatric and oncologic surgeons with additional anatomic data. We have examined 18 specimens of human fetuses (4-9 th month of PND, 82,0-311,0 mm of parieto-coccigeal length (PCL)). All material was obtained and studied at Chernivtsy Regional Pathologists Office (Ukraine) in accordance with bilateral collaboration with the Department of Histology, Cytology and Embryology of BSMU. To reach the aim of the research we have used classic morphological methods (anthropometry, morphometry, layered dissection) as well as injection of the blood vessels (in 6 specimens by the means of dies) and three-dimensional reconstructioning. The study was performed in accordance with the provisions of the Declaration of Helsinki on ethical issues of studies conducted with humans (1964-2008). We have seen that in fetal period of human PND (80,0-310,0 mm of PCL) ansa cervicalis, that provides innervation for infrahyoid structures, is formed by anastomosis of the superior and inferior roots (C2 and C3) that are merging with internal carotid artery and internal jugular vein. The infrahyoid muscles receive nourishment predominantly from the superior thyroid artery, that is a branch of external carotid artery (91 %) or rarely bifurcation (3 %) and either as a branch of common carotid artery (6 %). Specific feature of infrahyoid triangles during fetal period of PND is the fact that it highly relies on bony boundaries such as mandible, sternum and clavicle that haven't reached their mature morphology at 3 rd month of PND. Investigations of topographical peculiarities of structures in infrahyoid triangles in fetal period of PND are important for successful reconstruction surgeries in postnatal and adult age.

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Section: Discussionmentioning

confidence: 99%

Spatio-Temporal Morphological Changes of Structures in Infrahyoid Triangles in Human Fetuses During Fetal Period of Human Ontogenesis

2020

European Journal of Medicine

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“…In humans, the HLC shows a broad morphological variety in relation to its embryonic development [22,23]. Many differences have been described due to sex, race, age, and differences in body proportions [1,[24][25][26][27].…”

Section: The Hyoid-larynx Complexmentioning

confidence: 99%

“…Some anatomical variations can even mimic fractures. For example, non-fusion between the superior horn of the thyroid and thyroid body could incorrectly be identified as a fracture [23].…”

Section: The Hyoid-larynx Complexmentioning

confidence: 99%

Correction to: Fracture patterns of the hyoid-larynx complex after fatal trauma on the neck: retrospective radiological postmortem analysis of 284 cases

et al. 2020

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Purpose Fatal trauma on the neck occurs frequent in forensic cases and often results in fractures of the hyoid-larynx complex. The aim of the present study is to provide an overview of fractures in the hyoid-larynx complex that occur due to fatal trauma on the neck and can be observed by radiological evaluation. Methods Radiological images from a forensic radiological database created in the Groene Hart Hospital, Gouda, the Netherlands were used for analysis. Hyoid-larynx complexes were explanted in 284 individuals who accordingly to the forensic pathologist allegedly died from fatal trauma on the neck. These explants were imaged with conventional X-rays in eight directions and a CT scan. Radiological images were analyzed for fractures, dislocations, joints, and anatomical variations by a trained analyst and a radiologist. Results In 281/284 cases, the hyoid bone and, in 252/284 cases, the thyroid cartilage could be assessed. In 56 victims (20%), the hyoid bone was fractured, 55 times in the greater horn, 1 fracture in the body. The calcified superior horn of the thyroid showed a fracture in 101 victims (40%). The calcified cricoid cartilage was fractured in one case. Multiple fractures were found in 31/284 cases (11%). Joints between the greater horn and body of the hyoid were present in 74%. Key points 1. Thyroid cartilage superior horn fractures are most frequently found in fatal trauma on the neck. 2. Hyoid bone fractures most frequently occur in the greater horns. 3. Joints between the greater horn and the body of the hyoid bone were found in 74% of 281 cases. 4. Dislocations of hyoid joints are rare in fatal trauma on the neck victims (2,5%).

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“…One case was identified at the mandibular body, which contrastingly undergoes intramembranous ossification [30]. The hyoid also undergoes an endochondral-like process via mesenchymal condensation and fusion with the 2nd and 3rd pharyngeal arches [33].…”

Section: Reviewmentioning

confidence: 99%

Head and Neck Juxtacortical Chondrosarcoma: A Systematic Review

Jones¹,

Alwani²,

Summerlin³

et al. 2019

AOHNS

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Objective: To present a case and systematically evaluate trends in clinical presentation, imaging, histopathology, and management modalities and outcomes of all head and neck juxtacortical chondrosarcoma (HNJCS) cases reported in the existing literature. Methods: We describe a rare case of HNJCS from our tertiary referral center following which the PubMed, MEDLINE, Embase, and Web of Science databases were searched for all HNJCS reports. Relevant titles and abstracts were screened. Resulting full-text articles were assessed for eligibility, and remaining studies were included for data extraction, summarization, and analysis. Results: Potential studies were identified dating from May 1946 to February 2019. A total of nine cases were included in our systematic review, eight of which were identified from full-text articles and one recruited from our tertiary referral center. The median presentation age was 41 years with a 66.7% male preponderance. The commonest presenting sign was a painless, isolated swelling after a median symptom duration of 2.5 months. CT imaging revealed hypodense lesions with peripheral enhancement and micro-calcifications. T1-weighted MRI showed hypo-to iso-intense, lobulated masses with peripheral and/or septal enhancement. The masses were diffusely hyper-intense on T2-weighted MRI. Histopathology demonstrated septated lobules of malignant hyaline cartilage with a peripheral fibrous capsule. Most tumors were low-or intermediate-grade tumors with average diameter of 4.3 cm. Local recurrence was identified in only one case (four years after initial resection). No distal and/or nodal metastases were identified. All tumors were managed by wide-or narrow-margin surgical excision. Two reports employed adjuvant treatment. There was no evidence of disease at final follow-up (median of 1.5 years). Conclusion: To the best of our knowledge, only nine cases of HNJCS have been adequately described. HNJCS have relatively consistent clinical and diagnostic profile regardless of location in the body. Surgical management yields excellent outcomes with low recurrence rates.

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The development of the human hyoid–larynx complex revisited

Abstract: NA Laryngoscope, 1829-1834, 2018.

Cited by 26 publications

References 28 publications

Spatio-Temporal Morphological Changes of Structures in Infrahyoid Triangles in Human Fetuses During Fetal Period of Human Ontogenesis

Spatio-Temporal Morphological Changes of Structures in Infrahyoid Triangles in Human Fetuses During Fetal Period of Human Ontogenesis

Correction to: Fracture patterns of the hyoid-larynx complex after fatal trauma on the neck: retrospective radiological postmortem analysis of 284 cases

Head and Neck Juxtacortical Chondrosarcoma: A Systematic Review

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