The development and validation of the Treatment of Autoimmune Bullous Disease Quality of Life questionnaire, a tool to measure the quality of life impacts of treatments used in patients with autoimmune blistering disease

Abstract

We have shown that the TABQOL questionnaire is a valid and reliable instrument that may to be used to measure treatment burden in AIBD and serve as an end point in clinical trials.

Review of autoimmune blistering diseases: the Pemphigoid diseases

“…Mucocutaneous disease has significant impacts on the QoL of patients which may not be reflected on disease activity scoring systems. The autoimmune bullous disease QoL (ABQOL) and treatment of autoimmune bullous disease QoL (TABQOL) are validated tools which identify the impact the disease has on the patient's daily activities, work and relationships as well as the cost of medication, burden of taking the medication and anxiety about the underlying disease …”

Autoimmune blistering diseases in females: a review

“…In some studies, oral-health generic QOL measures such as Chronic Oral Mucosal Diseases Questionnaire (COMDQ) or psychiatric generic measures such as the 12-item General Health Questionnaire (GHQ-12) have also been used. However, none of those measures were disease-specific until the development of the Autoimmune Bullous Disease Quality of Life (ABQOL) questionnaire and the Treatment Autoimmune Bullous Disease Quality of Life (TABQOL) questionnaire by the Murrell group (Sebaratnam et al, 2013, Tjokrowidjaja et al, 2013). The ABQOL and TABQOL have both been shown as valid and reliable instruments for measuring QOL and treatment burden, respectively, in AIBDs.…”

The effect of autoimmune blistering diseases on work productivity

“…The ABQOL is more sensitive compared to the DLQI due to its higher content validity . The Treatment of Autoimmune Bullous Disease Quality of Life questionnaire (TABQOL) was developed from the pilot ABQOL questionnaire and assesses the impact of treatment on QoL …”