The deterioration in physical function of hemodialysis patients

Sutcliffe, Brianna K.; Bennett, Paul N.; Mohebbi, Mohammadreza

doi:10.1111/hdi.12570

Cited by 19 publications

(13 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…• Validated for people with chronic disease and used frequently in the dialysis population 32 Chair Timed-upand-go • Time in seconds for an adult to rise from sitting in a standard chair, walk 8 ft, turn, walk back to the chair. and sit down using regular footwear 49 • Validated in older adults and used frequently in the dialysis population 50 Chair and object at 8 ft Pinchstrength test-tip…”

Section: Discussionmentioning

confidence: 99%

“…

Physical Function Tests Test Details Equipment Figure Sit-to-stand Stand from a chair as many times as possible in 30 s 48 Validated for people with chronic disease and used frequently in the dialysis population 32 Chair Timed-up-and-go Time in seconds for an adult to rise from sitting in a standard chair, walk 8 ft, turn, walk back to the chair. and sit down using regular footwear 49 Validated in older adults and used frequently in the dialysis population 50 Chair and object at 8 ft Pinch-strength test-tip Seated on a chair without armrests, shoulder adducted, elbow flexed at 90°, forearm and wrist in neutral position Squeezed the pinch-grip dynamometer with thumb tip to index fingertip as hard as they could 3 measurements were repeated The highest score was recorded in kg 51 , 52 Pinch-grip dynamometer (PG-30, B&L Engineering) Pinch-strength test-lateral Seated on a chair without armrests, shoulder adducted, elbow flexed at 90°, forearm and wrist in neutral position Squeezed the pinch-grip dynamometer with thumb pad to lateral aspect of middle phalanx of index finger as hard as they could 3 measurements were repeated The highest score was recorded in kilograms 51 , 52 Pinch-strength test-palmar Seated on a chair without armrests, shoulder adducted, elbow flexed at 90°, forearm and wrist in neutral position Squeezed the pinch-grip dynamometer with thumb pad to pads of index and middle fingers as hard as they could 3 measurements were repeated The highest score was recorded in kg 51 , 52 Figures copyright Satellite Healthca...

…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

An Exercise Program for Peritoneal Dialysis Patients in the United States: A Feasibility Study

et al. 2020

Self Cite

View full text Add to dashboard Cite

Background People with end-stage kidney disease receiving peritoneal dialysis (PD) are generally physically inactive and frail. Exercise studies in PD are scarce and currently there are no PD exercise programs in the United States. The primary objective of this study was to test the feasibility of a combined resistance and cardiovascular exercise program for PD patients under the care of a dedicated home dialysis center in the United States. Study Design Parallel randomized controlled feasibility study. Setting & Participants PD patients were recruited from a single center and randomly assigned to the intervention (exercise; n = 18) or control (nonexercise; n = 18) group. Intervention The intervention group received monthly exercise physiologist consultation, exercise prescription (resistance and aerobic exercise program using exercise bands), and 4 exercise support telephone calls over 12 weeks. The control group received standard care. Outcomes The primary outcome was study feasibility as measured by eligibility rates, recruitment rates, retention rates, adherence rates, adverse events, and sustained exercise rates. Secondary outcome measures were changes in physical function (sit-to-stand test, timed-up-and-go test, and pinch-strength tests) and patient-reported outcome measures. Results From a single center with 75 PD patients, 57 (76%) were deemed eligible, resulting in a recruitment rate of 36 (63%) patients. Participants were randomly assigned into 2 groups of 18 (1:1). 10 patients discontinued the study (5 in each arm), resulting in 26 (72%) patients, 13 in each arm, completing the study. 10 of 13 (77%) intervention patients were adherent to the exercise program. A t test analysis of covariance found a difference between the treatment groups for the timed-up-and-go test ( P = 0.04) and appetite ( P = 0.04). No serious adverse events caused by the exercise program were reported. Limitations Single center, no blinded assessors. Conclusions A resistance and cardiovascular exercise program appears feasible and safe for PD patients. We recommend that providers of PD therapy consider including exercise programs coordinated by exercise professionals to reduce the physical deterioration of PD patients. Funding None. Trial Registration NCT03980795 .

show abstract

Section: Discussionmentioning

confidence: 99%

“…

…”

Section: Methodsmentioning

confidence: 99%

An Exercise Program for Peritoneal Dialysis Patients in the United States: A Feasibility Study

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…The frailty status of the HD population is broadly described in the literature (7,16,84), and recently many studies have analyzed the health status of the CKD population classified into different disease stages, and thus the relationship between CKD severity and frailty (29,(85)(86)(87)(88), slower gait speed (26), and decline in cognitive function (89) is becoming more evident. However, thus far the role of the transitional phase from predialysis to longterm dialysis in the frailty development process of patients with CKD is not well understood (32).…”

Section: Discussionmentioning

confidence: 99%

A Pilot Observational Study Assessing Long-Term Changes in Clinical Parameters, Functional Capacity and Fall Risk of Patients With Chronic Renal Disease Scheduled for Hemodialysis

et al. 2022

View full text Add to dashboard Cite

BackgroundPatients with end-stage renal disease are known to be particularly frail, and the cause is still widely seen as being directly related to specific factors in renal replacement therapy. However, a closer examination of the transitional phase from predialysis to long-term hemodialysis leads to controversial explanations, considering that the frailty process is already well-described in the early stages of renal insufficiency. This study aims to describe longitudinally and multifactorially changes in the period extending from the decision to start the replacement therapy through to the end of 2 years of hemodialysis. We hypothesized that frailty is pre-existent in the predialysis phase and does not worsen with the beginning of the replacement therapy. Between 2015 and 2018 we recruited 25 patients (72.3 ± 5.7 years old) in a predialysis program, with the expectation that replacement therapy would begin within the coming few months.MethodsThe patients underwent a baseline visit before starting hemodialysis, with 4 follow-up visits in the first 2 years of treatment. Health status, physical performance, cognitive functioning, hematology parameters, and adverse events were monitored during the study period.ResultsAt baseline, our sample had a high variability with patients ranging from extremely frail to very fit. In the 14 participants that did not drop out of the study, out of 32 clinical and functional measures, a statistically significant worsening was only observed in the Short Physical Performance Battery (SPPB) score (p < 0.01, F = 8.50) and the number of comorbidities (p = 0.01, F = 3.94). A careful analysis, however, reveals a quite stable situation in the first year of replacement therapy, for both frail and fit participants and a deterioration in the second year that in frail participants could lead to death.ConclusionOur results should stimulate a reassessment about the role of a predialysis program in reducing complications during the transitional phase, but also about frailty prevention programs once hemodialysis has begun, for both frail and fit patients, to maintain satisfactory health status.

show abstract

“…Na população idosa geral, quedas e resultados adversos associados, são um problema de saúde substancial associado a um risco significativo de morte 3 . Em pacientes com DRC em HD, as quedas também tem se tornado cada vez mais prevalentes e preocupantes, seja em pacientes idosos ou não [4][5][6][7] . Os fatores de risco associados ao risco de quedas aumentado em pacientes com DRC incluem a alta prevalência de comorbidades, múltiplas terapias medicamentosas, instabilidade hemodinâmica e metabólica induzida pela frequência do tratamento e fragilidade 8,9 .…”

Section: Introductionunclassified

A composição corporal está associada com o risco de quedas e medo de cair em pacientes em hemodiálise

Ribeiro¹,

Carvalho²,

Dourado³

et al. 2020

Rev Pesq Fisio

View full text Add to dashboard Cite

INTRODUÇÃO: Pacientes com doença renal crônica (DRC) submetidos à hemodiálise (HD) apresentam alterações musculoesqueléticas e de composição corporal que podem levar à redução do equilíbrio, velocidade de caminhada e capacidade de realizar as atividades de vida diária, aumentando o risco de quedas. OBJETIVO: associar o risco de quedas, medo de cair e composição corporal em pacientes com DRC submetidos à HD. MATERIAIS E MÉTODOS: estudo transversal com amostra de 40 pacientes em HD. Para o medo de cair e risco de quedas foram aplicados a Escala Internacional de Eficácia de Quedas e o QuickScreen Clinical Falls Risk Assessment. A amostra foi estratificada no percentil 50 para comparação da composição corporal de acordo com o risco de quedas e medo de cair. Para comparação entre os grupos, empregou-se o teste t de Student independente, e a correlação de Spearman para associar o risco de quedas e medo de cair com a composição corporal. O nível de significância adotado foi de p<0,05. RESULTADOS: correlação moderada positiva entre a gordura corporal com o medo de cair (r=0,47) e risco de quedas (r=0,42) e correlação moderada negativa entre a massa magra com o medo de cair (r=-0,51) e risco de quedas (r=-0,45). O grupo com maior risco de quedas apresentou maior gordura corporal (36,8±8,2 vs 30,9±6,9; p=0,043). O grupo com maior medo de cair obteve menor massa magra (41,6±9,2 vs 52,0±7,6; p=0,004). CONCLUSÃO: as variáveis de composição corporal associaram-se ao risco de quedas e ao medo de cair em pacientes com DRC submetidos à HD.

show abstract

The deterioration in physical function of hemodialysis patients

Abstract: Physical function significantly decreases on hemodialysis. Exercise programs to address this physical function decline should be included in hemodialysis treatment regimens.

Cited by 19 publications

References 44 publications

An Exercise Program for Peritoneal Dialysis Patients in the United States: A Feasibility Study

An Exercise Program for Peritoneal Dialysis Patients in the United States: A Feasibility Study

A Pilot Observational Study Assessing Long-Term Changes in Clinical Parameters, Functional Capacity and Fall Risk of Patients With Chronic Renal Disease Scheduled for Hemodialysis

A composição corporal está associada com o risco de quedas e medo de cair em pacientes em hemodiálise

Contact Info

Product

Resources

About