On October 12, 2005, a mysterious fog engulfed some parts of Lagos, the cause of which is yet to be identified. As part of the on-going scientific attempts to identify its cause, this article examines the contribution of anthropogenic combustion processes to oxides of nitrogen (NO x ), carbon monoxide (CO), sulphur dioxide (SO 2 ), and particulate matter (PM 10 ) in Lagos. On the average, predicted emissions are: NO x , 3.43 10 4 ; CO, 1.46 10 6 ; SO 2 , 1.24 10 3 ; and PM 10 , 7.84 10 3 ton/annum. Vehicular emissions from road transportation is an identified major source of criteria air pollutants in the city because combustion of gasoline in buses generated about 32% and 77% of the predicted NO x and CO emissions, respectively. Similarly, significant portions of predicted SO 2 emissions (57%) come from low pour fuel oil (LPFO) combustion. The highest emission of PM 10 from wood fuel combustion, which is 83%, raises some concern due to its potential impact on indoor air quality. Some control measures and identified area of future research in air pollution control in Lagos are suggested.