The dead bag syndrome

Werner, Liliana

doi:10.1097/j.jcrs.0000000000000930

Cited by 3 publications

(4 citation statements)

References 10 publications

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“…To allow a comparison between copolymers and, regarding previous published studies, the IOLs were analyzed in dry condition. 16 According to the work of Holland et al, and from empiric observations during testing, two principal ranges of mass loss were distinguished. 35 A first mass loss (L1) occurring from 20 to 150 C was calculated.…”

Section: Thermogravimetric Analysismentioning

confidence: 99%

“…It was been related to the manufacturing polishing processes of the surface. 16 The roughness was measured both in the center and on the edge of implants. Edges were studied as they could be an aging risk factor for PCO development.…”

Section: F I G U R Ementioning

confidence: 99%

“…These vacuoles can change the reflection of these lenses. [15][16][17] The phenomenon of surface light scattering has also been described in association with hydrophobic acrylic IOLs. Its mechanism may be related to longterm phase separation water near the IOL surface.…”

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confidence: 99%

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Comparative stability of intraocular lenses during 2–20 years of artificial aging, potential effects in terms of biocompatibility

Tortolano

Mrad

Manerlax

et al. 2022

J of Applied Polymer Sci

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Intraocular lenses (IOLs) are worldwide used for cataract surgery. Mostly made of acrylate polymers, they can lead to an unexpected biocompatibility reaction such as posterior capsular opacification (PCO). Acrylate polymers suffer from both oxidative and heat/thermal aging that affect their properties. We examined the stability of four currently available acrylic IOLs, three hydrophobic and one amphiphilic, under artificial aging that simulate intraocular conditions from 2 to 20 years. Released degradation products were detected by reversed‐phase high performance liquid chromatography. Thermal properties were investigated using thermogravimetric analysis, and differential scanning calorimetry measurements. Surface topography was analyzed by atomic force microscopy. The effect on biocompatibility was estimated with protein sorption of the aged lenses. Both surface and thermal properties changed under aging. Surface roughness of implants increased under aging in a kinetic in two steps. The aging also changed the polymer structure. These changes lead to a variable release of degradation products according to the chemical design of the copolymer. Glass temperature transition (Tg) and thermal degradation stability also suffered from aging. The aging has led to significant changes in protein sorption affinity to IOL surfaces. For pure hydrophobic acrylic copolymer, stability was higher for copolymers containing at least one fluoro methacrylate. The amphiphilic polymer appeared to have a time‐dependent aging that can affect the implant flexibility and could impact late biocompatibility reaction and tolerance.

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Section: Thermogravimetric Analysismentioning

confidence: 99%

Section: F I G U R Ementioning

confidence: 99%

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Comparative stability of intraocular lenses during 2–20 years of artificial aging, potential effects in terms of biocompatibility

Tortolano

Mrad

Manerlax

et al. 2022

J of Applied Polymer Sci

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“…4 In recent years, there has been an increase in reports of IOL dislocation many years after an uneventful cataract surgery with clear posterior capsule, termed as dead bag syndrome (DBS). 5 A case series of DBS after cataract surgery has been described by Culp et al 6 However, to the authors' knowledge, there is no report of a case of bilateral DBS. The authors believe that this is the first case report of bilateral DBS.…”

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confidence: 99%

Bilateral dead bag syndrome

Nayak,

Pai H,

2024

JCRS Online Case Rep

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Introduction: Posterior capsular rupture (PCR) is defined as breach in the continuity of the posterior part of the capsular bag in the human crystalline lens. Dead bag syndrome (DBS), a term coined by Samuel Masket, is a rare late complication of cataract surgery, which may present with spontaneous posterior capsular tear, causing intraocular lens (IOL) decentration or dislocation. It is usually seen in patients who have undergone an uneventful phacoemulsification with in-the-bag posterior chamber IOL implantation many years ago. Patient and Clinical Findings: A 73-year-old man presented with reduced vision in the right eye 17 years after an uneventful phacoemulsification and in-the-bag posterior chamber IOL implantation. There was no history of trauma to the eye. On examination, a decentered IOL with an inferior PCR was noted. Diagnosis, Intervention, and Outcomes: Decentered IOL was explanted, and a retro-iris–fixated IOL was implanted. Similar findings were noted in the left eye 4 years after the involvement of the right eye. There was no IOL dislocation or decentration. A diagnosis of DBS as the cause of PCR was made. The left eye was managed conservatively, and the patient remains under observation. Conclusions: The case described here seems to correspond to bilateral DBS. Physicians should be alert to look for the possibility of development of a similar complication in the other eye.

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Dead bag syndrome—in the capsular bag subluxated intraocular lens centration and refixation: A new technique

Thakur,

Bansal,

Challa

et al. 2023

Indian Journal of Ophthalmology

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We describe a technique of scleral IOL fixation and optic centration of in the capsular bag subluxated IOL in a patient of “dead bag syndrome.” A 29-year-old male diagnosed case of thalassemia presented with painless progressive diminution of vision in the left eye following uncomplicated sequential phacoemulsification in both eyes 15 years back. The right eye revealed completely centered IOL with significant amount of anterior capsular opacification (ACO), while the left eye revealed inferior subluxation of the IOL within capsular bag. The capsular bag was dilated, diaphanous with clear anterior and posterior capsule without any evidence of capsular fibrosis or opacification. Thus, a diagnosis of “dead bag syndrome” was made. The haptics were sutured to sclera (Hoffman’s pockets) using two loops of 9-0 polypropylene, passed anterior and posterior to IOL haptics within the capsular bag. Postoperatively, the patient had a vision of 20/40 with a centered intraocular lens.

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The dead bag syndrome

Cited by 3 publications

References 10 publications

Comparative stability of intraocular lenses during 2–20 years of artificial aging, potential effects in terms of biocompatibility

Comparative stability of intraocular lenses during 2–20 years of artificial aging, potential effects in terms of biocompatibility

Bilateral dead bag syndrome

Dead bag syndrome—in the capsular bag subluxated intraocular lens centration and refixation: A new technique

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