The Cyclopentolate Provocative Test in Suspected or Untreated Open‐angle Glaucoma

Valle, Olavi

doi:10.1111/j.1755-3768.1976.tb01277.x

Cited by 11 publications

(1 citation statement)

References 22 publications

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“…Mydriatic or cycloplegic agents can cause a rise in IOP, which might be related to decreased aqueous outflow, resulting from decreased pull on the trabecular meshwork due to ciliary muscle paralysis 26 . Valle 27 noted an increase in aqueous inflow in patients who experienced a rise in IOP following dilation and suggested a decrease in aqueous outflow in the same patients. It might well be that the variations in IOP seen in the present study represent a normal variation in how aqueous inflow and outflow are affected by tropicamide.…”

Section: Discussionmentioning

confidence: 97%

Transient changes of intraocular pressure and anterior segment configuration after diagnostic mydriasis with 1% tropicamide in children

Tsai

Kuo

et al. 2012

Clinical and Experimental Optometry

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Background: This study investigated the association of transient changes in intraocular pressure (IOP) with changes in the anterior chamber configuration in children after diagnostic mydriasis with 1% tropicamide. Methods: In this prospective case-control study, 163 hospital clinic-based samples of unrelated children with or without myopia were enrolled. Complete ophthalmological examinations, including visual acuities, cycloplegic refraction, slitlamp examination, fundus examination, IOP, axial length measurement and Pentacam examination were performed. Results: Lens thickness in emmetropic children was significantly greater than in myopic children of both genders, both before and after mydriasis. In a comparison of the biometric differences before and after mydriasis, IOP was not different, but the lens thickness after mydriasis was significantly less in myopic and emmetropic children of both genders. The mean anterior chamber angle, anterior chamber depth and anterior chamber volume significantly increased after mydriasis in myopic and emmetropic children of both genders. These parameters were not related to the changes of IOP under multiple regression analysis. There were no statistically significant differences between groups in either biometric parameters or anterior chamber configurations. Conclusion: While the present findings do not show a significant change in IOP following mydriasis, there was wide inter-individual variation, with some children showing an increase in IOP of up to 8.0 mmHg and some showing a decrease of a similar amount. This variation suggests that IOP should be monitored when mydriatics or cycloplegics are used in children.

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Section: Discussionmentioning

confidence: 97%

Transient changes of intraocular pressure and anterior segment configuration after diagnostic mydriasis with 1% tropicamide in children

Tsai

Kuo

et al. 2012

Clinical and Experimental Optometry

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The change in intraocular pressure after pupillary dilation in eyes with pseudoexfoliation glaucoma, primary open angle glaucoma, and eyes of normal subjects

et al. 2014

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To evaluate the change in intraocular pressure (IOP) after pharmacologic dilation in eyes with primary open angle glaucoma (POAG), pseudoexfoliation glaucoma (PXG), and eyes of normal subjects. This cross-sectional study was conducted in a university hospital-based setting. Patients with PXG, POAG, and normal subjects were consecutively selected and included in the study. Of the 125 eyes of 125 subjects; 46 (25 female) had PXG, 42 (29 female) had POAG, and 37 (20 female) belonged to the control group. Pharmacologic dilation procedure consisted of instillation of topical phenylephrine HCL 10 % followed 5 min by tropicamide 1 %. Studied variables were pre- and post-dilation IOP and also baseline measurements of anterior chamber angle, central corneal thickness, and pupillary diameter by Pentacam HR (Oculus, Wetzlar, Germany). Clinically significant IOP change was defined as a change of ≥2 mmHg from baseline. Randomly selected single eye of each patient was included in the analysis. The mean pre:post-dilation IOP of eyes with PXG and POAG was 17.39 ± 3.89:17.54 ± 3.98 and 15.92 ± 2.37:16.07 ± 2.89 mmHg, respectively. The difference between the pre- and post-dilation IOP of eyes with PXG and POAG was not statistically significant. The eyes of control subjects, however, had a statistically significant reduction of IOP from 14.24 ± 2.88 to 13.54 ± 2.94 mmHg (P = 0.005). 28.3 % (13/46) of eyes with PXG, 16.7 % (7/42) of eyes with POAG, and 2.7 % (1/37) of control eyes showed a clinically significant IOP elevation from baseline after the dilation. In this study, glaucoma patients proportionally experienced a higher rate of clinically significant IOP elevation after pupillary dilation, when compared to normal subjects.

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Two cases of acute intraocular pressure elevation with dabigatran use in glaucoma patients

Deleu¹,

Bremer²

2023

Journal Français d'Ophtalmologie

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The Cyclopentolate Provocative Test in Suspected or Untreated Open‐angle Glaucoma

Cited by 11 publications

References 22 publications

Transient changes of intraocular pressure and anterior segment configuration after diagnostic mydriasis with 1% tropicamide in children

Transient changes of intraocular pressure and anterior segment configuration after diagnostic mydriasis with 1% tropicamide in children

The change in intraocular pressure after pupillary dilation in eyes with pseudoexfoliation glaucoma, primary open angle glaucoma, and eyes of normal subjects

Two cases of acute intraocular pressure elevation with dabigatran use in glaucoma patients

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