The COVID-19 Pandemic, Part 1: Can Antimicrobial Copper-Based Alloys Help Suppress Infectious Transmission of Viruses Originating from Human Contact with High-Touch Surfaces?

Scully, John R.

doi:10.5006/3568

Cited by 35 publications

(35 citation statements)

References 25 publications

(47 reference statements)

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“…Copper alloy surfaces are also reported to possess anti-pathogenic performance, reducing the infectious disease transmission from fomites [132] , [134] , [135] , [136] , [137] . The surfaces of copper alloy, therefore, may limit the spread of COVID-19 [138] . As for comparison, COVID-19 could survive for three days on plastic and stainless steel surfaces, but no live COVID-19 could be detected on copper alloy surfaces only after four hours of exposure [139] .…”

Section: Application Of Nanotechnology In Virus Therapymentioning

confidence: 99%

Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

Seifi

Kamali

2021

Medicine in Drug Discovery

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Coronavirus disease-2019 has been one of the most challenging global epidemics of modern times with a large number of casualties combined with economic hardships across the world. Considering that there is still no definitive cure for the recent viral crisis, this article provides a review of nanomaterials with antiviral activity, with an emphasis on graphene and its derivatives, including graphene oxide, reduced graphene oxide and graphene quantum dots. The possible interactions between surfaces of such nanostructured materials with coronaviruses are discussed. The antiviral mechanisms of graphene materials can be related to events such as the inactivation of virus and/or the host cell receptor, electrostatic trapping and physico-chemical destruction of viral species. These effects can be enhanced by functionalization and/or decoration of carbons with species that enhances graphene-virus interactions. The low-cost and large-scale preparation of graphene materials with enhanced antiviral performances is an interesting research-direction to be explored.

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Section: Application Of Nanotechnology In Virus Therapymentioning

confidence: 99%

Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

Seifi

Kamali

2021

Medicine in Drug Discovery

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“…Besides Ag, Cu is also well-known for its antimicrobial properties [ 191 ], and thus, it can be used to reinforce the antimicrobial properties of polymer-based composites (in this work, we refer to examples where Cu is only used along with antimicrobial polymers, for other Cu-based antimicrobial systems, the readers are advised to look elsewhere [ 127 , 198 , 199 , 200 ]). Cu can kill bacteria by several mechanisms, including the release of Cu ions [ 201 ] or Cu NPs [ 202 ], as well as biofilm inhibition [ 203 ].…”

Section: Antimicrobial Surfaces Generated From Polymer-based Nanocompositesmentioning

confidence: 99%

Antimicrobial Polymeric Structures Assembled on Surfaces

2021

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Pathogenic microbes are the main cause of various undesired infections in living organisms, including humans. Most of these infections are favored in hospital environments where humans are being treated with antibiotics and where some microbes succeed in developing resistance to such drugs. As a consequence, our society is currently researching for alternative, yet more efficient antimicrobial solutions. Certain natural and synthetic polymers are versatile materials that have already proved themselves to be highly suitable for the development of the next-generation of antimicrobial systems that can efficiently prevent and kill microbes in various environments. Here, we discuss the latest developments of polymeric structures, exhibiting (reinforced) antimicrobial attributes that can be assembled on surfaces and coatings either from synthetic polymers displaying antiadhesive and/or antimicrobial properties or from blends and nanocomposites based on such polymers.

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“…In the case of copper alloys, copper ions in solution are produced from copper in the sequestered oxide layer formed over the surface of the alloy or released but chelated with some molecular species in solution [ 54 ]. Details of metallic corrosion processes producing biocide copper and the antimicrobial and antivirus effects of copper alloys are discussed by John R. Scully [ 55 ].…”

Section: Copper Alloy Touch Surfaces: An Effective Solution To Prementioning

confidence: 99%

Copper-Alloy Surfaces and Cleaning Regimens against the Spread of SARS-CoV-2 in Dentistry and Orthopedics. From Fomites to Anti-Infective Nanocoatings

et al. 2020

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The latest diffusion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the coronavirus disease (COVID-19), has involved the whole world population. Even if huge efforts to control the pandemic have been done, the viral spread is still continuing. COVID-19 is reported as a zoonosis jumped from bats and pangolins to humans. After infection in humans, SARS-CoV-2 is found in the nasopharyngeal and salivary secretions. The virus has also been detected in the blood plasma of infected patients. The viral spread occurs through droplets exhaled from the nose and mouth of the infected people when they breath or talk, or through droplets propelled as a dense cloud by chough or sneeze. The virus can also be delivered as an aerosol from blood plasma, through surgical procedures. Following these ways, the virus can disperse in the air, then reaching and settling on the exposed surfaces. How long the virus will survive on a surface depends on the material the surface is made from. Infection via high-touch surfaces should be prevented. Copper alloy coatings, combined with efficient hygienic/disinfectant procedures and careful surgical practice, could be helpful to health protection in dental practice and can also be adopted in orthopedic traumatology.

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The COVID-19 Pandemic, Part 1: Can Antimicrobial Copper-Based Alloys Help Suppress Infectious Transmission of Viruses Originating from Human Contact with High-Touch Surfaces?

Cited by 35 publications

References 25 publications

Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

Antimicrobial Polymeric Structures Assembled on Surfaces

Copper-Alloy Surfaces and Cleaning Regimens against the Spread of SARS-CoV-2 in Dentistry and Orthopedics. From Fomites to Anti-Infective Nanocoatings

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