2016
DOI: 10.17795/acr-41527
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The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population

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Cited by 2 publications
(2 citation statements)
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“…Autophagy, a cellular process that degrades unnecessary or dysfunctional components, including proteins and organelles, reduces the buildup of fatty deposits [14][15][16][17][18]. Its impact on cancer is intricate and contextdependent, as autophagy can both inhibit and promote tumor progression depending on the stage and environmental factors [17,19,20]. In ccRCC, enhancing autophagy activity may be benefcial, while defective autophagy could disrupt the balance of lipid storage and initiate ccRCC [21][22][23].…”
Section: Introductionmentioning
confidence: 99%
“…Autophagy, a cellular process that degrades unnecessary or dysfunctional components, including proteins and organelles, reduces the buildup of fatty deposits [14][15][16][17][18]. Its impact on cancer is intricate and contextdependent, as autophagy can both inhibit and promote tumor progression depending on the stage and environmental factors [17,19,20]. In ccRCC, enhancing autophagy activity may be benefcial, while defective autophagy could disrupt the balance of lipid storage and initiate ccRCC [21][22][23].…”
Section: Introductionmentioning
confidence: 99%
“…Colorectal carcinoma is a major cause of cancerassociated morbidity and mortality worldwide [1]. Despite the lower incidence of colorectal cancer in Asian countries in the past, recent studies point to its growing incidence in countries such as Iran [2][3][4]. According to annual reports, this type of cancer is the fifth and the third most common cancer in Iranian men and women, respectively [5,6].…”
Section: Introductionmentioning
confidence: 99%