The Correlation Between Fine Needle Aspiration Cytology and Histopathology of Head and Neck Lesions in Kathmandu University Hospital

Rajbhandari, M; Dhakal, Prasesh; Shrestha, Sandhya; Sharma, Shailendra; Pokharel, Manish; Shrestha, I; Shrestha, B; Makaju, R

doi:10.3126/kumj.v11i4.12525

Cited by 24 publications

(23 citation statements)

References 13 publications

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“…Rathod et al and Rajbhandari et al observed similar findings with maximum incidence of colloid goiter and then papillary carcinoma. 6,9 A study by Singal et al reported colloid goiter as the most commonly observed disorder in thyroid region similar to our finding. 10 Rout et al found colloid goiter as the most common among thyroid swelling followed by colloid goiter with cystic degeneration.…”

Section: Discussionsupporting

confidence: 91%

“…Other studies observed reactive lymphadenitis as the most common diagnosis of lymph node similar to our study. [9][10][11] In contrast, few studies showed tubercular lymphadenitis was the most frequent finding among lymph nodes. 1,2,[5][6][7] Out of 66 cases were available for HPE, NHL (27.3%) was the commonest pathological findings followed by granulomatous lymphadenitis (25.8%), metastatic carcinoma (19.7%), reactive lymphadenitis (10.6%), HL (7.6%), Kikuchi fujimoto disease (4.5%) and abscess (4.5%).…”

Section: Discussionmentioning

confidence: 97%

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Fine needle aspiration cytology of head and neck lesions and its correlation with histopathology

et al. 2016

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Background: Fine needle aspiration cytology is a minimally invasive technique used in the initial diagnosis of different types of lesions located in head and neck region commonly originating from cervical lymph node, thyroid gland, salivary glands and soft tissues. The objective of this study was to evaluate the diagnostic accuracy, sensitivity and speci city of FNAC in various head and neck lesions in correlation with their histopathological examination. Materials and methods: A hospital based prospective study was conducted among 209 patients with palpable head and neck region swellings in the Department of Pathology, Bhaktapur Cancer Hospital and the Department of Pathology, Nepal Medical College from August 2014 to July 2015. FNAC were done from palpable masses of head and neck regions. Data entry and analysis were done using SPSS 17. Result: There were 209 FNAC cases enrolled, out of which lymph node lesions (n=128) were the most common lesions followed by thyroid (n=40), other soft tissues (n=27) and salivary gland (n=14). Reactive lymph nodes, colloid goiter, epidermoid cyst and sialadenosis were the predominant diagnosis of lymph nodes, thyroid gland, soft tissues and salivary gland respectively. Highest accuracy, sensitivity and speci city were observed in thyroid gland, salivary gland and soft tissues. However, four false negative results for malignancy were reported in lymph node lesions. Conclusion: Head and neck region swellings are the commonly encountered conditions. FNAC being highly accurate, sensitive and speci c makes it useful and reliable procedure for screening and diagnosis of palpable masses in head and neck region.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 97%

Fine needle aspiration cytology of head and neck lesions and its correlation with histopathology

et al. 2016

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“…False negative cases may be explained by degenerative changes or the intensity of inflammation or hemorrhage leading to misinterpretation . The presence of a mixed population of lymphoid tissues and tingible body macrophages suggest reactive lymphoid hyperplasia but don't definitively rule out lymphomas or other malignancies . FNAC has been proved to be a reliable diagnostic tool in the detection of lymph node malignancies with good sensitivity and specificity as demonstrated by our study.…”

Section: Discussionmentioning

confidence: 68%

Accuracy of fine‐needle aspiration cytology of head and neck masses

Rammeh

Romdhane

Sassi

et al. 2018

Diagnostic Cytopathology

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Background Head and neck masses are a common presentation in daily practice and can be challenging to both clinicians and cytopathologists. Fine needle aspiration cytology (FNAC) is a widely used method for the diagnosis of head and neck masses. The aim of the study was to assess our institutional experience of the accuracy of FNAC in the diagnosis of head and neck masses. Methods A total of 1262 FNACs were conducted from January 2013 to December 2016 and subdivided into benign and malignant categories. The thyroid and salivary glands FNACs were classified according to the Bethesda System for Reporting Thyroid cytopathology and to the Milan System for Reporting Salivary Gland Cytopathology respectively. The measures of diagnostic accuracy of FNAC were determined taking histology as a gold standard. Results A total of 7 false negative (FN) and 6 false positive (FP) FNACs were identified. Overall sensitivity and specificity of FNAC for a malignant diagnosis were 92% and 94.4%, respectively. Accuracy of FNACs of head and neck masses was 93.5% for all sites. The salivary gland group had the highest rate of FN (2.8%). All FP were reported in the thyroid group. These cases were cytologically classified suspicious for malignancy (n = 3) and papillary carcinoma (n = 3) and proved to be lymphocytic thyroiditis on final histology. Among the most common locations, cytology of lymph nodes provided the best sensitivity (98.2%). Salivary glands as well as lymph nodes had the best specificity (100%). Conclusion FNAC of head and neck masses has a high accuracy allowing a correct therapeutic management. However, this accuracy depends on the anatomic location of the mass.

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“…8,9 The whole spectrum of biopsied head and neck lesions include a variety of differential diagnosis ranging from 10 In the present study, a total of 145 cases were analysed.…”

Section: Discussionmentioning

confidence: 99%

Histopathological patterns of head and neck lesions - a two year retrospective hospital based study

Sharma¹,

Sharma²,

Gandhi³

et al. 2017

Int J Res Med Sci

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Background: Head and neck lesions include a spectrum of pathological lesions ranging from simple benign to highly malignant entities. These lesions contribute significantly to morbidity and mortality of patients. The aim of this study was to determine the histological patterns of head and neck lesions, both non- neoplastic and neoplastic and to analyse the data in relation to age, gender, topography.Methods: A two year retrospective study was conducted in the Post Graduate Department of Pathology, ASCOMS and Hospital and histopathological data pertaining to all head and neck lesions was reviewed. Each case was analysed with respect to age, gender, site and histological type.Results: One hundred and forty-five cases from the head and neck region were analysed during this two-year period. Age range was from 3 months to 85 years with maximum cases in the age group of 21-50 years (51.03%). The Male: Female ratio was 1.37:1. In our study, 53.79% benign, 24.13% inflammatory and 22.06% malignant cases were recorded. Maximum number of benign lesions was in the age group of 21-50 years. Malignancies were noted to be higher in ages 51 years and above. Squamous cell carcinoma was the most common malignancy observed.Conclusions: We conclude that site specific data like this is helpful in evaluating patterns of head and neck lesions and augment the base line data of institute and the region.

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The Correlation Between Fine Needle Aspiration Cytology and Histopathology of Head and Neck Lesions in Kathmandu University Hospital

Cited by 24 publications

References 13 publications

Fine needle aspiration cytology of head and neck lesions and its correlation with histopathology

Fine needle aspiration cytology of head and neck lesions and its correlation with histopathology

Accuracy of fine‐needle aspiration cytology of head and neck masses

Histopathological patterns of head and neck lesions - a two year retrospective hospital based study

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