The coordination chemistry of mono(di-2-pyridylamine) copper(II) complexes with monovalent and divalent oxoanions: crystal structure, spectroscopic and magnetic properties of dinuclear [Cu(L)(μ-H2PO4)(H2PO4)]2 and polynuclear [Cu(L)(μ3-HPO4)]n

Youngme, Sujittra; Phuengphai, Pongthipun; Chaichit, Narongsak; Pakawatchai, Chaveng; Albada, Gerard A. van; Roubeau, Olivier; Reedijk, Jan

doi:10.1016/j.ica.2004.04.027

Cited by 19 publications

(10 citation statements)

References 37 publications

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“…The first two, at around 1090 and 991 cm −1 , are assigned to the asymmetric and symmetric stretching of the PO 2 − groups; these two bands have been already reported for pyridoxal phosphate . The third band appears in the region 849–791 cm −1 , and is associated with ν (P−OH) and ρ (PO−H) vibrations, in agreement with evidence found for some copper complexes . Finally, the peak at 546 cm −1 in 1 is attributed to the δ (O−P−O) normal mode, and is observed at higher wavenumbers than the same band in K 2 H 10 L⋅2.5 H 2 O.…”

Section: Resultssupporting

confidence: 86%

Self‐Assembly of Manganese(II)–Phytate Coordination Polymers: Synthesis, Crystal Structure, and Physicochemical Properties

et al. 2017

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myo‐Inositol phosphates are an important group of biomolecules that are present in all eukaryotic cells. The most abundant member of this family in nature is InsP6 (phytate, L12− in its fully deprotonated form). Phytate interacts strongly with inorganic and organic cations, and this interaction is essential for determining the possible functions of this biomolecule. Herein, the chemical, thermodynamic, and structural characterization of phytate–MnII species is presented in a study aimed at understanding how the interaction of the two components modulates their biological roles and their bioavailability. Polynuclear complexes Mn5(H2L)⋅16 H2O (1) and (H2terpy)2[Mn(H6L)(terpy)(H2O)]⋅17 H2O (terpy=terpyridine) (2) were prepared and characterized by different techniques. The isolation of 1 and the determination of its solubility, together with potentiometric titrations of the MnII–phytate system, allow the full description of this binary system. The preparation and crystal structure of 2 show a novel coordination mode of phytate, that is, the formation of infinite polymeric chains through equatorial phosphate groups.

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Section: Resultssupporting

confidence: 86%

Self‐Assembly of Manganese(II)–Phytate Coordination Polymers: Synthesis, Crystal Structure, and Physicochemical Properties

et al. 2017

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“…In the Casiopeína III-ia coordination compound the copper (II) ion is able to coordinate with the phosphate species (HPO 4 2− or H 2 PO 4 − ) replacing the water molecule and therefore it is able to form hydrogen phosphate bridges with other Casiopeína III-ia aggregates. These hydrogen phosphate bridges have been reported for coordination compounds with copper (II) as the metallic center [15–17], and also with other coordination compounds where the metallic centers are vanadium and zirconium [18, 19]. These hydrogen phosphate bridges could also explain the reason why in our calorimetric studies we found a higher value of ∆H D for the dissociation of the Casiopeína III-ia aggregates in the buffer media in comparison with the pure water media.…”

Section: Resultssupporting

confidence: 79%

Investigation on the self-association of an inorganic coordination compound with biological activity (Casiopeína III-ia) in aqueous solution

Marín-Medina

García‐Ramos

Ruíz-Azuara

et al. 2016

Chemistry Central Journal

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From studies using different experimental techniques employed to determine the presence of aggregates e.g. isothermal titration calorimetry, surface tension, electrical conductivity, UV–Vis spectrophotometry, dynamic and static light scattering, it is clearly demonstrated that the compound [Cu(4, 4′-dimethyl-2, 2′-bipyridine)(acetylacetonato)H2O]NO3 (Casiopeína III-ia), promising member of a family of new generation compounds for cancer treatment, is able to auto associate in aqueous media. Physicochemical properties associated with the formation of the aggregates were determined in pure water and in phosphate buffer media in order to simulate physiological conditions. From isothermal titration calorimetry and electrical conductivity measurements we calculated the dissociation constant of the aggregates, K D. For pure water the values obtained in both techniques are 2.73 × 10−4 and 5.93 × 10−4 M respectively while for the buffer media we obtained 4.61 × 10−4 and 1.57 × 10−3 M. The enthalpy of dissociation, ∆H D, calculated from the calorimetric data shows that the presence of the phosphate ions has an energetic effect on the aggregate stability since in pure water a value of 18.79 kJ mol−1 was obtained in comparison with the buffer media where a value 4 times bigger was found (70.48 kJ mol−1). With the data collected from these techniques the number of monomers calculated which participate in the formation of the aggregates is around two. From our surface tension, electrical conductivity and UV–Vis spectrophotometry measurements the critical aggregate concentration, cac, was determined. For each technique specific concentration ranges were obtained but we can summarize that the cac in pure water is between 3 and 3.5 mM and for the buffer media is between 3.5 and 4 mM. Dynamic light scattering measurements provide us with the hydrodynamic diameter of the aggregates and from static light scattering measurements we determined the molecular weight of the Casiopeína III-ia aggregates to be of 1000.015 g mol−1 which is two times the molecular weight of the Casiopeína III-ia molecule. This value is in agreement with the number of monomers which participate in the formation of the aggregates obtained from isothermal titration calorimetry and electrical conductivity data analysis.

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“…The fact that g || > g ⊥ > 2⋅00 showed that the unpaired electron is in the d x2-y2 orbital of copper(II) and the complex is a distorted square-based pyramidal geometry. 33 The hyperfine structure is well resolved for the complex. The spectrum of trinuclear copper complex, reveals four lines in the g ║ region which are assigned to the interaction of the paramagnetic electron with the Cu(II) nucleus (I = 3/2); however, the intensity pattern of the lines is complex.…”

Section: Magnetic and Esr Studiesmentioning

confidence: 96%

Synthesis, characterization and extraction studies of N,N″-bis[1-biphenyl-2-hydroxyimino-2-(4-acetylanilino)-1-ethylidene]-diamines and their homo-and heteronuclear copper(II) complexes

2009

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A new series of homo-and heteropolynuclear copper(II) complexes of N,N″-bis[1-biphenyl-2-hydroxyimino-2-(4-acetylanilino)-1-ethylidene]-diamines have been prepared and characterized by different physical techniques. The starting point of the research was the reaction of chloroacetyl chloride with biphenyl in the presence of aluminum chloride. 4-Biphenylhydroximoyl chloride was obtained by reacting synthesized 4-(chloroacetyl)biphenyl with alkyl nitrite. Substituted 4-(alkylaminoisonitrosoacetyl)biphenyl (ketooxime) was prepared by reacting 4-biphenylhydroximoyl chloride with 4-aminoacetophenone in EtOH. Homodi-, homotrinuclear and heterodinuclear copper(II) perchlorate complexes of tetradentate Schiff bases which possess N 4 donor sets derived from the condensation of 4-(arylaminoisonitrosoacetyl)biphenyl and diamine derivatives were synthesized and characterized. Elemental analysis, FT-IR, ESR, molar conductivity, magnetic moment measurements and thermal analyses studies were utilized for the investigation of the complexes. The free ligands were also characterized by 1 H-and 13 C-NMR spectra. Elemental analyses, stoichiometric and spectroscopic data of the metal complexes indicated that the metal:ligand ratio of dinuclear copper(II) complexes were found to be 2 : 1 while this ratio was 3 : 2 in trinuclear copper(II) complexes and the metal complexes indicated that the metal ions are coordinated to the oxime and imine nitrogen atoms. The extraction abilities of the novel ligands were also evaluated in chloroform by using several transition metal picrates such as Mn 2+ , Co 2+ , Ni 2+ , Cu 2+ , Zn 2+ , Pb 2+ , Cd 2+ , Hg 2+ . It has been observed that both ligands show a high affinity to Cu 2+ ions.

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The coordination chemistry of mono(di-2-pyridylamine) copper(II) complexes with monovalent and divalent oxoanions: crystal structure, spectroscopic and magnetic properties of dinuclear [Cu(L)(μ-H2PO4)(H2PO4)]2 and polynuclear [Cu(L)(μ3-HPO4)]n

Cited by 19 publications

References 37 publications

Self‐Assembly of Manganese(II)–Phytate Coordination Polymers: Synthesis, Crystal Structure, and Physicochemical Properties

Self‐Assembly of Manganese(II)–Phytate Coordination Polymers: Synthesis, Crystal Structure, and Physicochemical Properties

Investigation on the self-association of an inorganic coordination compound with biological activity (Casiopeína III-ia) in aqueous solution

Synthesis, characterization and extraction studies of N,N″-bis[1-biphenyl-2-hydroxyimino-2-(4-acetylanilino)-1-ethylidene]-diamines and their homo-and heteronuclear copper(II) complexes

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