The control of glycolysis in early embryogenesis

Mil'man, L S; Yurowitzki, Yu.G.

doi:10.1016/0304-4165(67)90132-8

Cited by 14 publications

(2 citation statements)

References 23 publications

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“…Also, Milman & Yurowitzky (1967) were able to demonstrate in early embryogenesis a considerable (three-fold) increase in glycolysis in v i v a Immediately after fertilization there was a significant decrease in glycogen, in accordance with the findings of Yurowitzky & Milman (1975) of an acceleration of glycogenolysis after fertilization in Misgurnus fossilis (Linnaeus, 1758).…”

Section: Discussion and Conclusion Embryonic Developmentsupporting

confidence: 85%

Carbohydrate metabolism during embryonic and larval development of Odonthestes humensis(De Buen, 1953) (Pisces—Atherinidae)

Santos

Vinagre

1991

Journal of Fish Biology

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Changes in glucose and glycogen concentrations during embryonic and larval development of Odonthestes humensis (De Buen, 1953) (Pisces-Atherinidae) were followed.Glycogen decreased immediately after fertilization but remained constant throughout the embryonic period, suggesting that although present glycogenolisis may not be the most important energetic pathway during this period. Glucose levels only show a significant increase on the fifth day of development coincident with the beginning of heart activity. In fed larvae glycogen utilization increases during development, resulting in an increase in glucose concentration. Such a pattern does not occur in starved animals, where glycogen and glucose are present respectively at high and low concentrations similar to embryos. The change of pattern seems to be associated with the first larval feeding.

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Section: Discussion and Conclusion Embryonic Developmentsupporting

confidence: 85%

Carbohydrate metabolism during embryonic and larval development of Odonthestes humensis(De Buen, 1953) (Pisces—Atherinidae)

Santos

Vinagre

1991

Journal of Fish Biology

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“…First, early development is often fueled by anaerobic metabolism. Glycolysis has been shown to play a significant metabolic role during early development, especially during cleavage and blastulation (Hishida and Nakano, '54; Crawford and Wilde, '66; Milman and Yurowitzky, '67). This early ability to depend on anaerobic pathways to support development is thought to be largely a byproduct of the metabolism of dormant oocytes before fertilization, which are known to fuel metabolism using predominately glycolytic pathways (Boulekbache, '81).…”

Section: Discussionmentioning

confidence: 99%

Aerobic and anaerobic capacities differ in embryos of the annual killifish Austrofundulus limnaeus that develop on alternate developmental trajectories

Chennault

Podrabsky

2010

J. Exp. Zool.

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Embryos of the annual killifish Austrofundulus limnaeus have a remarkable tolerance to anoxia during their development, especially during diapause II (DII), but little is known about potential mechanisms by which this tolerance is achieved. This study examined the aerobic and anaerobic capacities of these embryos as they develop along alternate developmental trajectories and in response to altered incubation temperature. Aerobic and anaerobic capacities were estimated by measuring the total activity of the enzymes citrate synthase (CS) and lactate dehydrogenase (LDH), respectively. Embryos of A. limnaeus exhibit high anaerobic capacity throughout development as evidenced by high LDH/CS ratios, especially during early development through DII. Anaerobic production of lactate is supported by the heart isoform of LDH, even in stages of development that exhibit extreme tolerance of anoxia. CS capacity is extremely low during DII and may indicate an active suppression of mitochondrial metabolism during this stage of dormancy. Post-DII and "escape" embryos which bypass DII increase their aerobic and anaerobic capacities in tandem as they develop. The activity of both LDH and CS continue to increase for many days after morphological development ceases during DIII. Based on this observation, it is likely that regulation of metabolic dormancy is different in DII and III. Escape embryos seem to develop along a different metabolic trajectory than do embryos that enter diapause. Importantly, these embryos complete development with different enzymatic capacities that could influence physiological and ecological performance during early larval life.

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Calorespirometry of developing embryos and yolk-sac larvae of turbot (Scophthalmus maximus)

1995

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The control of glycolysis in early embryogenesis

Cited by 14 publications

References 23 publications

Carbohydrate metabolism during embryonic and larval development of Odonthestes humensis(De Buen, 1953) (Pisces—Atherinidae)

Carbohydrate metabolism during embryonic and larval development of Odonthestes humensis(De Buen, 1953) (Pisces—Atherinidae)

Aerobic and anaerobic capacities differ in embryos of the annual killifish Austrofundulus limnaeus that develop on alternate developmental trajectories

Calorespirometry of developing embryos and yolk-sac larvae of turbot (Scophthalmus maximus)

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