The Control Level of Bronchial Asthma in Dependence of Genotype by BCL1 Polymorphism of Glucocorticoids Receptor Gene and Body Mass Index

Abstract

The frequency of allelic genotypes by BclI polymorphism glucocorticoids receptor gene (GR) had been studied in dependence of the control level of bronchial asthma (BA) and body mass index (BMI), and also-connection between those indicators.188 patient with BA and 95 almost healthy humans were investigated. Determination of single nucleotide BclI polymorphism GR gene performed by the method of polymerase chain reaction with following analyze of the length of restriction fragments.