The content and effectiveness of physical activity for cancer‐related fatigue among colorectal cancer survivors: Systematic review and meta‐analysis

Abstract

Colorectal cancer (CRC) is the third most frequent cancer globally; according to the latest data, the incidence of new colorectal cancer cases was as high as 10%, and the number of new cases worldwide reached 1.93 million in 2020 (Sung et al., 2021). One of the most common treatment options for CRC in clinical practice is radical resection combined with chemotherapy, which has greatly improved the survival rate (Iveson et al., 2019). However, the quality of life of CRC patients has not been promoted significantly due to the many adverse effects caused by cancer itself and treatments, especially chemotherapy, such as chronic pain, sleep disturbances, fatigue, depression and so on (Ketelaers et al., 2022;Sakr et al., 2020).Therefore, the burden of follow-up care for CRC survivors is expected to increase, and exploring ways to improve cancer-related symptoms and quality of life in this population deserves attention.Cancer-related fatigue (CRF), a sustained and distressing sense of tiredness or exhaustion, is currently recognized as one of the