The Connection between Celiac Disease and Hepatic Steatosis: High Levels of Pigment Epithelium-Derived Factor

Dikker, Okan; Dağ, Hüseyi̇n

doi:10.1159/000503633

Cited by 2 publications

(2 citation statements)

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“…Inflammation mediates the interplay in the pathogenesis of coeliac disease and hepatic steatosis, and they may be interconnected with a common background. 20 For the diagnosis of coeliac disease, serum tissue anti-transglutaminase-IgA (tTG-IgA) and endomysium-IgA (EMA-IgA) antibodies can be investigated. Both have similar sensitivities and have a high negative predictive value in patients with a low suspicion of coeliac disease.…”

Section: Nafld and Inve S Ti G Ati On Of Comorb Iditie Smentioning

confidence: 99%

“…Previous studies have shown that fatty liver disease is frequent in patients with coeliac disease, and in contrast, coeliac disease is also more common in patients with hepatic steatosis. Inflammation mediates the interplay in the pathogenesis of coeliac disease and hepatic steatosis, and they may be interconnected with a common background 20 . For the diagnosis of coeliac disease, serum tissue anti‐transglutaminase‐IgA (tTG‐IgA) and endomysium‐IgA (EMA‐IgA) antibodies can be investigated.…”

Section: Nafld and Investigation Of Comorbiditiesmentioning

confidence: 99%

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Current management of NAFLD/NASH

Cardoso

Figueiredo-Mendes

Villela-Nogueira

et al. 2021

Liver International

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NAFLD is the most common cause of liver disease worldwide, and its prevalence is significantly increasing. Studies have shown that it is associated with comorbidities such as diabetes, metabolic syndrome and obesity. Early diagnosis and management are highly important and could modify the prognosis of the disease. Evaluating the possibility of multiple aetiologies and recognizing the additional causes of liver disease should be a part of the patient's initial assessment. There are no approved drug treatments as yet, so the main management strategies should involve lifestyle changes such as physical activity and dietary re‐education.

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Section: Nafld and Inve S Ti G Ati On Of Comorb Iditie Smentioning

confidence: 99%

Section: Nafld and Investigation Of Comorbiditiesmentioning

confidence: 99%