The comparison of the radiation load to the heart and the left anterior descending coronary artery for various modes of radiation treatment of the breast cancer patients

Бондаренко, Андрій Володимирович; Корытова, Л И; Маслюкова, Е А; Korytov, Oleg; Muravnik, E.M.

doi:10.17650/1994-4098-2016-12-3-10-16

Cited by 3 publications

(2 citation statements)

References 25 publications

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“…Radiation doses per lung with exposed supraclavicular and infraclavicular LN in dorsal position with tidal respiration or breathhold were similar. In addition, based on our previous research, it was outlined that cardiac radiation exposure in prone position was the worst [4]. Thus, patients' prone positioning is more suitable for right-sided patients, so that in this case heart is not exposed to irradiation, and exposure reduction per lung is beneficial.…”

Section: Discussionmentioning

confidence: 99%

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The Estimation of the Radiation Dose to the Left Lung for Various Modes of Conformal Radiation Treatment of the Breast Cancer Patients

Корытова¹,

Maslyukova²,

Бондаренко³

et al. 2017

RAD Conference Proceedings

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Abstract. Lowest dose detection per ipsilateral lung versus various dosimetric irradiation plans for the left mammary gland is investigated. The study involves dosimetric radiotherapeutic (RT) plans of 20 female patients with left BC (breast cancer). Pre-irradiation preparation included 3 sessions of CT scan: patient in standard dorsal position with tidal respiration (STR), in dorsal position with controlled breathhold on top inspiration (DBH) and in prone position with tidal respiration (PTR). Three CT-sessions were followed by 3D-plan dosimetric calculations. Dose-volumetric measures for organs at risk (OAR) were assessed for every irradiation option. Contoured left lung volume in all studied variants varied within 757.1 cm 3 -2923.8 cm 3 , mean volume 1751.6 cm 3 . The best values, such as V25lung (when α/β=3.1) and V28lung (when α/β=9), average doses per ipsilateral lung were received using the PTR method (V25lung (α/β=3.

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Section: Discussionmentioning

confidence: 99%

“…Manifestations vary from incidental radiological findings to respiratory gross lesions in patients with expressed clinical manifestations. The symptoms of acute radial pulmonitis are routinely expressed in 2-3 months after radiotherapy, but they can also appear in a month or 6 months after treatment termination [1,4,5].…”

Section: Introductionmentioning

confidence: 99%

The Estimation of the Radiation Dose to the Left Lung for Various Modes of Conformal Radiation Treatment of the Breast Cancer Patients

Корытова¹,

Maslyukova²,

Бондаренко³

et al. 2017

RAD Conference Proceedings

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Development of radiation therapy for breast cancer

Salim¹,

Shonus²,

Stolbovoy³

2017

Onkol. Z. im. P.A. Gercena

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Тему лучевого лечения рака молочной железы (РМЖ) не перестают обсуждать на научных съездах и страницах онкологических журналов. Это понятно, ведь облучение, как и хирургическая операция, высокоэффективная и до сих пор неотъемлемая часть противоракового лечения. Лечение ионизирующим излучением в различных вариантах используется при РМЖ от нулевой (TisN0M0) до IV стадии. Лечение РМЖ имеет более чем вековую историю. С него началось использование ионизирующего излучения в лечебных целях. Первый сеанс лечения РМЖ провел Эмиль Груббей (Emil Grubbe) в 1896 г. в Чикаго, о чем он написал в журнале «Radiology» в 1933 г. [1], но до сих пор мы обсуждаем, какова должна быть мишень у тех или иных больных, какая методика облучения для них более всего подходит и какой режим фракционирования наиболее успешен. Эти направления поддерживаются сохраняющимся высоким уровнем заболеваемости и смертности от РМЖ и высокой социальной значимостью болезни. В онкологической среде нет необходимости говорить о важности лучевого компонента в лечении, однако в менее специализированных учреждениях его нередко недооценивают как врачилечебники, так и врачи-администраторы. Это приводит к ошибкам в составлении планов комбинированного и комплексного

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Radiation-Induced Damage to the Cardiovascular System After Radiation Therapy in Women With Breast Cancer

Bazyka

Lytvynenko

Demianov

2022

Probl Radiac Med Radiobiol

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Despite current research in the development of drug-based cytostatic and targeted therapies in the treatment of breast cancer, radiation therapy (RT) is an important component in the treatment of this pathology in the postoperative period. At the same time, an important problem is the development of pathological changes in the heart in the long-term period, which worsen the quality of life and increase the risk of cardiac death 10 or more years after RT The problem of heart damage due to RT is gaining new significance due to the existing increase in the number of cancer patients requiring radiation exposure in the modern world. RT of malignant tumors of the breast and organs of the chest cavity causes damage to all structures of the heart, including the coronary arteries, valves, conducting system, pericardium. The frequency of heart damage increases in proportion to the time that has passed after RT. According to some authors, the prevalence of clinically significant radiation-induced heart diseases 5–10 years after RT is 10–30 %, and the frequency of asymptomatic lesions is 88 %. The duration of the latent period can reach 15–20 years. The work has an analysis of long-term studies of the presence of pathological changes that are found in the heart tissues of patients with breast cancer, as a result of radiation therapy. Key words: breast cancer, radiation therapy, adjuvant radiation therapy, radiation damage to the heart.

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The comparison of the radiation load to the heart and the left anterior descending coronary artery for various modes of radiation treatment of the breast cancer patients

Abstract: ОПУХОЛИ ЖЕНСКОЙ РЕПРОДУКТИВНОЙ СИСТЕМЫ TUMORS OF FEMALE REPRODUCTIVE SYSTEM method (4.25 %, 3.13 Gy, 1.3 Gy, respectively) in comparison with FB (9.49 %, 4.96 Gy, 1.95 Gy, respectively) and PP (12.8 %, 9.06 Gy, 24.18 Gy, respectively)

Cited by 3 publications

References 25 publications

The Estimation of the Radiation Dose to the Left Lung for Various Modes of Conformal Radiation Treatment of the Breast Cancer Patients

The Estimation of the Radiation Dose to the Left Lung for Various Modes of Conformal Radiation Treatment of the Breast Cancer Patients

Development of radiation therapy for breast cancer

Radiation-Induced Damage to the Cardiovascular System After Radiation Therapy in Women With Breast Cancer

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