The Combined Adrenal Suppression and Ovarian Stimulation Test in Patients with the Stein-Leventhal Syndrome

Hart, P.G.; Bakker, J. H. J.; Molen, H. J. van der

doi:10.1159/000302331

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Stimulation/suppression Tests1

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1986

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“…Similarly, dexamethasone-suppressibility of serum T has been plagued by questions of specificity and is still the subject of an ongoing controversy. 3,5,[302][303][304][305][306][307][308][309][310][311][312][313][314][315][316][317][318] Although complete dexamethasone suppression of serum T (to less than 20 ng/dl) renders an ovarian hyperandrogenic source unlikely and suggests an ACTH-dependent adrenal disorder, several investigators proposed that dexamethasone may not be adrenal-selective and that it may also be capable of inhibiting ovarian androgen biosynthesis. 3,5,306,319 Consequently, dexamethasone suppressibility of serum T need not necessarily be equated with adrenal hyperandrogenism.…”

Section: Stimulation/suppression Testsmentioning

confidence: 99%