The Clinical Value of the Treponema Immobilization Test in the Diagnosis and Control of Syphilis

Studies on the Treponemal Immobilization Test

“…in 106 patients with early latent syphilis and none in twenty cases of late latent syphilis; Miller and others (1952) found no T.P.I.negative cases among 37 patients with early latent and only nine in 213 patients with late latent syphilis (these nine patients all had positive or weakly positive S.T.S. ); Chacko (1953) found nine patients out of 101 with treated latent syphilis to have negative immobilization tests.…”

“…Examination of published reports shows, however, that only relatively small numbers of tests on sera from presumed normal persons or from patients with diseases other than syphilis have been reported by individual workers. Thus, Nelson and others (1950) found negative results in 101 normal persons and in 107 with diseases other than syphilis; Magnuson and Thompson (1949) found that 73 normal patients and 81 with diseases other than syphilis all gave negative results; Miller and others (1952) reported negative results in thirteen normal persons and in seventy with diseases other than syphilis; Chacko (1953) found no positive results among 241 nonsyphilitic sera; Sequeira (1954) examined 256 sera from pregnant women and found two which gave positive T.P.I. tests but negative S.T.S.…”