“…New vaccines for rabies and for plague are under development, along with a vaccine for coccidioidomycosis. Of further interest immunologically is the development of a specific Treponema pallidum immobilization test for more precise serologic diagnosis of syphilis (15). Although complicated, and not yet employed by many laboratories, the test appears to be of value in the detection of false-positive and negative complement-fixation reactions and may offer a solution to this diagnostic problem in the management of syphilis.…”