The clinical specular microscope

Binkhorst, C.D.; Loones, L. H.; Nugaard, P.

doi:10.1016/s0146-2776(77)80057-8

Cited by 8 publications

(3 citation statements)

References 21 publications

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“…Specular microscopy has been used for many years with a common application being to examine the corneal endothelium before and after intraocular surgery to assess whether cell loss has occurred (Binkhorst et al. , 1977; Edelhauser, 2000).…”

Section: Introductionmentioning

confidence: 99%

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A comparison of two methods for estimating polymegethism in cell areas of the human corneal endothelium

Doughty¹,

Oblak²

2008

Ophthalmic Physiologic Optic

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Section: Introductionmentioning

confidence: 99%

“…, 1989). Such a difference in cell density, arising from regional differences in cell areas, is usually referred to as polymegethism, which can also occur after intraocular surgery (Binkhorst et al. , 1977; Edelhauser, 2000).…”

Section: Introductionmentioning

confidence: 99%

A comparison of two methods for estimating polymegethism in cell areas of the human corneal endothelium

Doughty¹,

Oblak²

2008

Ophthalmic Physiologic Optic

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“…Determination of endothelial cell density using the specular microscope has become increasingly valuable in the study of effects of various medications, chemicals or surgical procedures on the structure and function of the corneal endothelium (Binkhorst et al 1977;Hirst et al 1977). Several studies have identified and evaluated sources of measurement error (Sperling & Gunderson 1978;Azen et al 1980).…”

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Variation in Central and Vertical Corneal Endothelial Cell Density in Normal Subjects

Azen

Burg

Reinig

1981

Acta Ophthalmologica

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Twenty normal subjects, aged 20 to 50, who had never worn contact lenses underwent determinations of central, inferior and superior corneal endothelial cell density using the Heyer-Schulte specular microscope. Analysis of variance revealed that superior cell density was significantly larger than central cell density, and that central cell density was significantly larger than inferior cell density (P less than 0.00001). In addition, 4 of these subjects had measurements taken on 4 separate sessions. Analysis of variance revealed that central and vertical cell density determinations were reproducible across measurement sessions. The finding of a vertical gradient in cell density was in contrast to 2 published reports which found no vertical differences in the normal cornea. Consequently, those data were re-analyzed using correct statistical procedures and similar vertical differences were obtained for one series of patients. The finding of a vertical gradient in endothelial cell density challenges the appropriateness of relying upon measurement of the central corneal field as an indicator of the pre-operative endothelial cell density.

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Clinical Specular Microscopy and Intraocular Surgery

Abbott¹,

Forster²

1979

Archives of Ophthalmology

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The clinical specular microscope

Cited by 8 publications

References 21 publications

A comparison of two methods for estimating polymegethism in cell areas of the human corneal endothelium

A comparison of two methods for estimating polymegethism in cell areas of the human corneal endothelium

Variation in Central and Vertical Corneal Endothelial Cell Density in Normal Subjects

Clinical Specular Microscopy and Intraocular Surgery

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