The Clinical Spectrum of Granulomatous Prostatitis: A Report of 200 Cases

Abstract

Granulomatous prostatitis, reviewed in 200 tissue-diagnosed cases, occurred in 0.8 per cent of the benign inflammatory prostatic specimens. Often the disease followed a recent urinary tract infection (71 per cent) and was suspicious clinically for prostatic cancer (59 per cent). The diagnosis usually was made by needle biopsy or at transurethral prostatectomy (94 per cent). Most cases of granulomatous prostatitis were classified as nonspecific. The recently identified entity of post-transurethral resection granulomatous prostatitis was found in 49 patients. A proposed new category of granulomatous prostatitis that is secondary to systemic granulomatous diseases was documented in 6 patients. Most cases of granulomatous prostatitis resolved spontaneously and required no specific therapy.

A rare case of granulomatous prostatitis caused by Mycobacterium tuberculosis

“…It is also well described that in patients with granulomatous prostatitis, the prostate gland is clinically firm and nodular on digital rectal examination and mimics carcinoma. 2,3,7,8,15 Our patient had similar findings on clinical examination.…”

“…[4][5][6] Nonspecific granulomatous prostatitis is the most common type, accounting for 60-80% cases of granulomatous prostatitis as reported in the literature. [6][7][8] Infective granulomatous prostatitis can be caused by Mycobacterium tuberculosis, nontuberculous mycobacteria, Treponema pallidum, viruses, and fungal organisms. [9][10][11] …”

Granulomatous prostatitis diagnosed during intravesical BCG treatment

“…Rectal examinations disclose abnormality specific to prostatitis. [6,7] Diagnosis of prostatitis is made with histopathological examination of the biopsy specimens retrieved because of suspect prostate cancer. In our case, diagnosis was made by histopathological examination of the prostate biopsy specimens harvested because of suspect prostate cancer after detection of increased PSA levels, and abnormal DRE findings.…”

A peculiar case of granulomatous prostatitis: a cause for concern

“…The condition may mimic prostatic malignancy, both clinically and histologically [1]. PSA levels may rise but this increase is elevation must be followed up after appropriate counselling and only after careful assessment of the histology with appropriate immunohistochemistry.…”

“…The condition may mimic prostatic malignancy, both clinically and histologically [1]. PSA levels may rise but this increase is as infection, retention and instrumentation [2].…”