The Clinical Features of Rheumatoid Arthritis

Ragan, Charles

doi:10.1001/jama.1962.03050340001001

Cited by 96 publications

(18 citation statements)

References 8 publications

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“…Few workers have suggested that a particular site of early joint disease is of prognostic significance.9 20 We could not show that the site of disease at onset was predictive, but clearly subsequent early wrist and MTP joint disease carried a worse prognosis. Nine well-defined patterns of disease were revealed by factor analysis,22 including one based on wrist, elbow, shoulder, and knee and one based on MTP joints I and II.…”

Section: Discussioncontrasting

confidence: 56%

Prognostic value of early features in rheumatoid disease

Corbett¹

1976

BMJ

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Section: Discussioncontrasting

confidence: 56%

Prognostic value of early features in rheumatoid disease

Corbett¹

1976

BMJ

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“…Serum HA levels were also higher at baseline in seropositive patients than in seronegative patients. This may reflect the relationship between positive R F and more severe disease (28)(29)(30).…”

Section: Discussionmentioning

confidence: 99%

Serum hyaluronate level as a predictor of radiologic progression in early rheumatoid arthritis

Paimela

Heiskanen

Kurki

et al. 1991

Arthritis & Rheumatism

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PATIENTS AND METHODSRA patients. Forty consecutive patients (31 women, 9 men) with newly diagnosed definite or classic RA (according to the 1958 criteria of the American Rheumatism Association [9]) were included in the study. The mean duration of disease in the RA patients at the beginning of the study was 7.0 months (range 2-12 months). The mean age of the patients was 41.5 years (range 19-61). At the time of diagnosis, 27 of the patients (67.5%, 18 women and 9 men) were

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“…This pattern of disease, where the infl ammatory burden is substantial, affects less than 5% of patients. 13 Whe n encountered, such manifestations typically prompt extensive investigations for alternative diagnoses, especially malignancy.…”

Section: Rheumatoid Arthritismentioning

confidence: 99%

The ying and yang of fever in rheumatic disease

Galloway

Cope

2015

Clinical Medicine

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Fevers are relatively common in rheumatic disease, largely due to the fact that the infl ammatory process is driven by infl ammatory mediators that function as endogenous pyrogens. Since the immune system's sensors cannot accurately distinguish between endogenous and exogenous (pathogen-derived) pyrogens a major challenge for physicians and rheumatologists has been to decipher patterns of clinical signs and symptoms to inform clinical decision making. Here we describe some of the common pitfalls and clinical challenges, and highlight the importance of a systematic approach to investigating the rheumatic disease patient presenting with fever.

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The Clinical Features of Rheumatoid Arthritis

Cited by 96 publications

References 8 publications

Prognostic value of early features in rheumatoid disease

Prognostic value of early features in rheumatoid disease

Serum hyaluronate level as a predictor of radiologic progression in early rheumatoid arthritis

The ying and yang of fever in rheumatic disease

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