The Clinical and Radiological Presentation of Spinal Dural Arteriovenous Fistula

Muralidharan, Rajanandini; Saladino, Andrea; Lanzino, Giuseppe; Atkinson, John L.D.; Rabinstein, Alejandro A.

doi:10.1097/brs.0b013e31821352dd

Cited by 110 publications

(116 citation statements)

References 23 publications

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“…17 These lesions are thought to be acquired conditions and affect predominantly middle-aged men; at least 80% of patients in most series are male. 15,18,20,22,26,30 Aside from speculation about genetic influence, the reason for such a strong male predominance is unknown. The average age at diagnosis is 58-63 years, and more than two-thirds of patients are in the 6th or 7th decade of life at the time of diagnosis.…”

Section: Epidemiologymentioning

confidence: 99%

Clinical presentation and prognostic factors of spinal dural arteriovenous fistulas: an overview

Fugate¹,

Lanzino

Rabinstein³

2012

FOC

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Spinal dural arteriovenous fistulas (AVFs), the most common type of spinal cord vascular malformation, can be a challenge to diagnose and treat promptly. The disorder is rare, and the presenting clinical symptoms and signs are nonspecific and insidious at onset. Spinal dural AVFs preferentially affect middle-aged men, and patients most commonly present with gait abnormality or lower-extremity weakness and sensory disturbances. Symptoms gradually progress or decline in a stepwise manner and are commonly associated with pain and sphincter disturbances. Surgical or endovascular disconnection of the fistula has a high success rate with a low rate of morbidity. Motor symptoms are most likely to improve after treatment, followed by sensory disturbances, and lastly sphincter disturbances. Patients with severe neurological deficits at presentation tend to have worse posttreatment functional outcomes than those with mild or moderate pretreatment disability. However, improvement or stabilization of symptoms is seen in the vast majority of treated patients, and thus treatment is justified even in patients with substantial neurological deficits. The extent of intramedullary spinal cord T2 signal abnormality does not correlate with outcomes and should not be used as a prognostic factor.

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Section: Epidemiologymentioning

confidence: 99%

Clinical presentation and prognostic factors of spinal dural arteriovenous fistulas: an overview

Fugate¹,

Lanzino

Rabinstein³

2012

FOC

Self Cite

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“…Also in accordance with previous studies, most SDAVFs in our series originated from the thoracic and lumbar levels. 14,22,23 Several prior studies have reported results after endovascular treatment of SDAVFs. Niimi et al, 25 reported 49 patients who were primarily treated with n-BCA, but isobutyl-2-cyanoacrylate and polyvinyl alcohol were also used.…”

Section: Discussionmentioning

confidence: 99%

“…Most of the patients in our study were males 77.3% (17 patients) with an average age of 59.3± 9.7.This finding also correlates with the demographics seen in several other large studies. 14,19,23 We had only one patient younger than 40 years in our study, which illustrates the rarity of this diagnosis in the younger patient population.…”

Section: Discussionmentioning

confidence: 99%

“…12,13,19 The delay to diagnosis in our patients 23.9 months (range, 6-36 months) is comparable to other series. 11,13,14,23 We did not correlate the severity of the clinical presentation with the time of diagnosis. Most of the patients in our study were males 77.3% (17 patients) with an average age of 59.3± 9.7.This finding also correlates with the demographics seen in several other large studies.…”

Section: Discussionmentioning

confidence: 99%

“…These symptoms at clinical presentation are similar to those reported in other large series. 11,14,23,24,32 Development of upper motor neuron signs with gait and micturition impairment is usually seen late in the course of the disease process. Early diagnosis and successful treatment of the fistula correlates with improvement in clinical symptoms.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Spinal Dural Arteriovenous Fistulas: Clinical and Radiological outcome of Endovascular Treatment

Habib¹,

Abdelaal²

2014

Egyptian Spine Journal

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Background Data: Spinal dural arteriovenous fistulas are a rare entity that, if left untreated, can lead to considerable morbidity. Early diagnosis and effective methods of treatment are badly needed in clinical application. Purpose: To evaluate the clinical and radiological outcome of patients with spinal dural arteriovenous fistulas who were treated with endovascular embolization, with assessment of feasibility, safety and efficacy of endovascular treatment. Study Design: A retrospective clinical case study. Patients and Methods: A retrospective study was conducted on patients with Spinal Dural Arteriovenous Fistulas (SDAVFs) who underwent endovascular treatment in the period between

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Exercise-Associated Numbness and Tingling in the Legs

Sharp

Pride²,

Mathis

et al. 2011

Arch Neurol

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52-year-old physically active man with a medical history of coronary artery disease, hypertension, and hyperlipidemia presented with numbness and tingling in the legs. His symptoms were intermittent initially, triggered by running or playing soccer and relieved by rest. Symptoms progressed during 1 year. The numbness became more constant, and he developed leg pain radiating from the popliteal fossa to the heel bilaterally (pain was more severe in the left leg compared with the right leg). Recently, he had noted some constipation as well as difficulty in initiating urination.

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The Clinical and Radiological Presentation of Spinal Dural Arteriovenous Fistula

Cited by 110 publications

References 23 publications

Clinical presentation and prognostic factors of spinal dural arteriovenous fistulas: an overview

Clinical presentation and prognostic factors of spinal dural arteriovenous fistulas: an overview

Spinal Dural Arteriovenous Fistulas: Clinical and Radiological outcome of Endovascular Treatment

Exercise-Associated Numbness and Tingling in the Legs

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