2020
DOI: 10.1590/0037-8682-0205-2020
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The clinical and molecular diagnosis of childhood and adolescent pulmonary tuberculosis in referral centers

Abstract: Introduction: The diagnostic accuracy of Xpert MTB/RIF (Xpert) in pulmonary tuberculosis (PTB) in children is lower than in adults. In Brazil, the diagnosis of PTB is based on a diagnostic score system (DSS). This study aims to study the role of Xpert in children and adolescents with PTB symptoms. Methods: A cross-sectional study was conducted in 3 referral centers to TB. Children and adolescents (0-19 years old) whose respiratory samples were submitted to Xpert were included. Statistical analysis (bivariate a… Show more

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Cited by 2 publications
(4 citation statements)
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“…The difficulties in diagnosis, contact tracing, and access to health care facilities would explain this challenge from a public health standpoint. 7 , 42 …”
Section: Diagnosis Of Tuberculosis In Childrenmentioning
confidence: 99%
See 2 more Smart Citations
“…The difficulties in diagnosis, contact tracing, and access to health care facilities would explain this challenge from a public health standpoint. 7 , 42 …”
Section: Diagnosis Of Tuberculosis In Childrenmentioning
confidence: 99%
“…Studies have addressed malnutrition as either a cause or a consequence of tuberculosis, depending on the epidemiological scenario in question. 42 …”
Section: Diagnosis Of Tuberculosis In Childrenmentioning
confidence: 99%
See 1 more Smart Citation
“…In recent years, molecular diagnostic techniques have become widely used in the diagnosis and epidemiological investigation of infection by bacteria of the mycobacterium tuberculosis complex (MTBC). ( Carpentier et al., 1995 ; Detjen et al., 2015 ; Aurilio et al., 2020 ) The Xpert MTB/RIF method is recommended by the WHO for rapid diagnosis of TB, replacing the traditional time-consuming culture method.…”
Section: Introductionmentioning
confidence: 99%