The cleanliness differences of root canal irrigated with 0.002% saponin of mangosteen peel extract and 2.5% NaOCl

Sakinah, Anis; Setyowati, Laksmiari; J, Devi Eka

doi:10.20473/j.djmkg.v48.i2.p104-107

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…Kelebihan lain dari kalsium hidroksida adalah dapat merangsang pembentukan jaringan keras. 15,16 Perlakuan irigasi saluran akar dengan menggunakan akuades steril tidak menunjukkan pergaruh terhadap tingkat ketahanan fraktur pada dinding saluran akar karena akuades tidak mengandung zat kimia dan hanya berfungsi membersihkan saluran akar saja. Hal ini dibuktikan oleh Syafira pada kelompok kontrol yang diirigasi dengan akuades, hanya berfungsi membasahi saluran akar.…”

Section: Pembahasanunclassified

Differences in fracture resistance after root canal irrigation using guava leaf extract (Psidium guajava L.) and lime juice (Citrus aurantifolia)

Arifin

Anas

Nursakia

2022

MDJ

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After root canal treatment, teeth are at higher risk of fracture than vital teeth; the cause is multifactorial, both iatrogenic and non-iatrogenic. Guava are often usedbecause the leaves have been proven to treat various diseases. Guava leaves contain active ingre-dients, including tannins, flavonoids, essential oils and saponins.Lime is often processed by the community as a fresh drink, such as warm lime juice. Lime fruit has useful ingredients such as essential oils, citric acid, amino acids and saponins. The aim of this study was to analyze differences in fracture resistance after root canal irrigation between 60% GL extract and 100% lime juice. This is a laboratory experiment using extracts of GL, LJ, maxillary central incisor with a post-test only control group design, which was tested statistically by using one-way Anova followed by a post hoc test. Fracture resistance in the 60% GL extract group averaged is 45.07±9.80; while the 100% LJ group is40.86±12.71; the differ is 4,280. It was concluded that there is no significant difference in the degree of fracture resistance between the 60% GL and 100% LJextract groups as root canal irriga-gation materials.

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Section: Pembahasanunclassified

Differences in fracture resistance after root canal irrigation using guava leaf extract (Psidium guajava L.) and lime juice (Citrus aurantifolia)

Arifin

Anas

Nursakia

2022

MDJ

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Effectiveness of brown algae extract (Sargassum sp) 15% in dissolving root canal smear layer (a SEM study)

Trilaksana

Kirana

Arisandi

2020

Medicina Clínica Práctica

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Formulation and Characterization of a Novel Palm-Oil-Based α-Mangostin Nano-Emulsion (PO-AMNE) as an Antimicrobial Endodontic Irrigant: An In Vitro Study

et al. 2023

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Aim: To formulate and characterize a palm-oil-in-water-based α-Mangostin nano-emulsion (PO-AMNE) endodontic irrigant, in order to evaluate its antibacterial efficacy against Enterococcus faecalis, Staphylococcus epidermidis, and Candida albicans biofilms, as well as its capacity to remove smear layer. Methods: The solubility of α-Mangostin in various oils was determined and selected, surfactants and co-surfactants were used for the nano-emulsion trial. PO-AMNE was prepared and optimized. The MIC was performed, and the antimicrobial efficacy was estimated against biofilms. The optimized 0.2% PO-AMNE irrigant antimicrobial efficacy in a tooth model was done using colony-forming units. The treated teeth were processed by scanning electron microscopic examination for debris and smear layer removal. An Alamar Blue assay was used to evaluate cell viability. The optimization of the PO-AMNE irrigant was performed using Box–Behnken statistical design. Results: The optimized 0.2% PO-AMNE irrigant was found to have a particle size of 340.9 nm with 0.246 PDI of the dispersed droplets, and a zeta potential (mV) of −27.2 ± 0.7 mV. The MIC values showed that 0.2% PO-AMNE (1.22 ± 0.02) were comparable to 2% CHX (1.33 ± 0.01), and 3.25% NaOCl (2.2 ± 0.09) had the least inhibition for E. faecalis. NaOCl (3.25%) showed the maximum inhibition of S. epidermidis (0.26 ± 0.05), whereas 0.2% PO-AMNE (1.25 ± 0.0) was comparable to 2% CHX (1.86 ± 0.07). For C. albicans, 2% CHX (8.12 ± 0.12) showed the least inhibition as compared to 0.2% PO-AMNE (1.23 ± 0.02) and 3.25% NaOCl (0.59 ± 0.02). The 0.2% PO-AMNE irrigant was then evaluated for its antimicrobial efficacy against the three biofilms, using colony-forming units. The 0.2% PO-AMNE was comparable to both 3.25% NaOCl and 2% CHX in inhibiting the growth of biofilms. The 0.2% PO-AMNE and 17% EDTA eliminated the smear layer with the lowest mean scores (p < 0.001). Finally, 0.2% PO-AMNE was shown to be biocompatible when compared to 17% EDTA, 3.25% NaOCl, and 2% CHX in immortalized oral keratinocyte cells. Conclusion: Overall, the formulated 0.2% PO-AMNE irrigant was an effective antimicrobial and biocompatible which could combat endodontic-infection-related polymicrobial biofilms.

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The cleanliness differences of root canal irrigated with 0.002% saponin of mangosteen peel extract and 2.5% NaOCl

Cited by 3 publications

References 6 publications

Differences in fracture resistance after root canal irrigation using guava leaf extract (Psidium guajava L.) and lime juice (Citrus aurantifolia)

Differences in fracture resistance after root canal irrigation using guava leaf extract (Psidium guajava L.) and lime juice (Citrus aurantifolia)

Effectiveness of brown algae extract (Sargassum sp) 15% in dissolving root canal smear layer (a SEM study)

Formulation and Characterization of a Novel Palm-Oil-Based α-Mangostin Nano-Emulsion (PO-AMNE) as an Antimicrobial Endodontic Irrigant: An In Vitro Study

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