“…Moreover, thecatenin/TCF complex is known to cooperate with AP-1 for maximum expression. 14) While there are a large number of reports regarding MMP-9 suppressants, including catechins, 15) curcumin, 16) 1,25-dihydroxyvitamin D 3 , 17) peroxisome proliferator-activated receptor (PPAR) activators, 18) inhibitors of cyclooxygenase (COX) and phospholipase A 2 , 19) and nobiletin (NOB), [20][21][22][23] those for MMP-7 are limited (e.g., retinoic acid, 24) butyrate, 25) and PPAR agonist troglitazone 26) ). In the present study, we investigated the expression of MMPs in human colorectal cancer cell lines and found a high level of MMP-7 mRNA in HT-29 cells.…”