The circaseptan variation of stroke onset – a hospital-based study

Abstract

Introduction. Circaseptan or weekly rhythm, despite not belonging to terrestrial rhythms and being a conventional one, influences the incidence of stroke through short-term lifestyle changes. Objectives. To investigate the presence of a weekly variation pattern in the onset of cerebrovascular pathology in patients admitted to Neurology Departments I and II of the County Hospital Cluj-Napoca over the course of 2012. Material and method. The study is based on demographic data, data referring to the day of onset, the type of stroke and the subtype of ischemic stroke, collected retrospectively from the observation sheets of 1083 patients with stroke admitted through the Emergency Room to Neurology Departments I and II of the County Hospital Cluj-Napoca. Diagnosis was defined according to updated World Health Organization criteria and the Trial of ORG 10172 in Acute Stroke Treatment Classification. Results and conclusions. The circaseptan variation of stroke onset reveals two incidence peaks, one over the weekend continuing through Monday, and one in the middle of the week. Age, sex and the type/subtype of stroke enhances one of these peaks.

The influence of circadian variation in ischemic stroke onset on the evolution of the severity of the clinical picture and disability

“…Over the past years, interest has increased in the study of chronobiological aspects involved in health maintenance as well as in the development of various diseases. The study of the temporal variation in the incidence of cerebrovascular pathology is part of this interest (1)(2)(3)(4). Ischemic stroke describes a circadian variation pattern with the highest incidence in the morning, according to most literature reports (5)(6)(7)(8)(9).…”