The Chinese version of the Severe Respiratory Insufficiency questionnaire for patients with chronic hypercapnic chronic obstructive pulmonary disease receiving non-invasive positive pressure ventilation

Abstract

ObjectivesThe Severe Respiratory Insufficiency (SRI) questionnaire is the best assessment tool for health-related quality of life in patients with chronic obstructive pulmonary disease (COPD) receiving non-invasive positive pressure ventilation (NIPPV). This study aimed to translate the SRI Questionnaire into Chinese and to validate it.DesignProspective validation study.Setting and participantsA total of 149 participants with chronic hypercapnic COPD receiving NIPPV completed the study.MethodsThe SRI questionnaire was translated into Chinese using translation and back-translation. Reliability was gauged using Cronbach’s α coefficient. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were used to assess construct validity. Content validity was confirmed by evaluating the relationship between the score of each item and the total score of the relevant subscale.ResultsCronbach’s α coefficients for each subscale and summary scale were above 0.7. Using EFA, one factor was extracted from the anxiety and summary scales and two factors were extracted from the remaining six subscales. Based on the EFA results, subsequent CFA revealed a good model fit for each subscale, but the extracted factors of each subscale were correlated. Content validity was confirmed by the good relationship between the score of each item and the total score of the relevant subscale.ConclusionThe Chinese version of the SRI questionnaire is valid and reliable for patients with chronic hypercapnic COPD receiving NIPPV in China.Trial registration numberNCT02499718.

Chinese version of the severe respiratory insufficiency questionnaire for patients with COPD receiving long-term oxygen therapy

“…However, the Cronbach’s α coefficient for SRI-AS approximately reached 0.7, which was acceptable and higher compared with other versions of the SRI. 9 , 12 – 18 Moreover, a previous study demonstrated that the Cronbach’s α coefficients for the German SRI ranged from 0.69 to 0.93 when used for COPD patients with LTOT, 11 which was similar to our study. The differences between that study and our study were that our sample size was larger and all of our patients were both hypoxemic and hypercapnic.…”

“…Translation of the Chinese version of the SRI was consistent with the translation and backtranslation procedure described in our previous study. 18 First, the original version of the SRI was independently translated into Chinese by two translators. A committee comprising the two translators and the project manager examined both forward translations and reconciled them into a single forward translation.…”

“…The SRI was originally developed in German 9 and has been translated into many languages, including English, Spanish, Norwegian, French, Portuguese, Japanese, and Chinese. 12 – 18 Our team previously translated the SRI into Chinese and showed that it has a good reliability and validity for patients with COPD undergoing long-term noninvasive ventilation. 18 To date, no published work has demonstrated whether the Chinese version of the SRI can be used for patients with COPD undergoing LTOT.…”

“… 12 – 18 Our team previously translated the SRI into Chinese and showed that it has a good reliability and validity for patients with COPD undergoing long-term noninvasive ventilation. 18 To date, no published work has demonstrated whether the Chinese version of the SRI can be used for patients with COPD undergoing LTOT. Therefore, the purpose of this study aimed to evaluate the reliability and validity of the Chinese version of the SRI in assessing the quality of life among Chinese patients with COPD undergoing domiciliary LTOT.…”

The specificity and definition of blood eosinophil

“…Various artificial intelligence methods have been applied in the COPDGene and ECLIPSE studies. [3][4][5][6] For example, deep learning with deep belief network has been applied to classify exacerbation frequency in COPDGene. 5 However, the goal of our study was to specifically examine the role of blood eosinophils in AECOPD, because blood eosinophil measurement is a widely available clinical test, and there are potential treatments for eosinophilic COPD.…”