The Chemistry of Nickel‐Containing Enzymes

Crystal structure of diaquabis(6-hydroxy-3-pyridazinecarboxylato)- nickel(II) dihydrate, Ni(H2O)2(C5H3N2O3)2 · 2H2O

“…Thus rigid carboxylate ligands have been widely used for the design and synthesis of avariety of structures [4]. Among these carboxylatebase complexes, nickel(II) representatives have attracted great attention since nickel has been recognized as aconsiderably important biological agent forming the active site of av ariety of metalloproteins, such as hygrogenase (H 2-ase), carbon monoxide dehydrogenase (CODH), S-methyl-coenzyme Mm ethylreductase (MCR) and urease [5,6]. In addition, their adducts with nitrogen have potential applications in area of organic conductors and magnetic materials [7].…”

Crystal structure of bis[1-(2-hydroxybenzylidene)thiosemicarbazido]- nickel(II) dinitrate, [Ni(C8H9N3OS)2](NO3)2

“…These complexes can serve as potent antitumor, antiviral and antibacterial agents [5]. Among these Schiff-base complexes, nickel(II) representatives have attracted great attention since nickel has been recognized as aconsiderably important biological agent forming the active site of avariety of metalloproteins, such as hygrogenase(H 2 -ase), carbon monoxide dehydrogenase (CODH), S-methyl-coenzyme-M methylreductase (MCR) and urease [6][7][8]. In addition, their adducts with nitrogen have potential applications in area of organic conductors and magnetic materials [9].…”

Speciation studies of Co(II), Ni(II) and Cu(II) complexes of L-valine in acetonitrile–water mixtures

“…Acetonitrile also acts as a strongly differentiating solvent with a modest solvating power for many polar ionic solutes (Aktas et al, 2006). Co(II), Ni(II) and Cu(II) are associated with several enzymes and any variation in their concentrations leads to metabolic disorders (Kolodziej, 1994). Hence, the speciation of Co(II), Ni(II) and Cu(II) complexes of L-valine in varying compositions of acetonitrile-water mixtures have been studied.…”