The Chemistry of Cell Division: I. The Effect of Glutathione on Cell Division in Amoeba Proteus

The Effect of Amino Acids Upon Cell Division in Ustilago

“…Other work has shown that various chemical agents may affect cell division, though the mechanisms of these effects are not clearly understood. The SH compounds were reported early by Voegtlin and Chalkley (1930) and by Rapkine (1937) to be involved in cell division processes. Webb (1953) has shown the need for magnesium in bacterial division, and Nickerson and Van Rij (1949) have described the effects on yeast of agents such as cobalt, penicillin, cysteine and glutathione.…”

“…Webb (1953) has shown the need for magnesium in bacterial division, and Nickerson and Van Rij (1949) have described the effects on yeast of agents such as cobalt, penicillin, cysteine and glutathione. The SH compounds were reported early by Voegtlin and Chalkley (1930) and by Rapkine (1937) to be involved in cell division processes. Many chemicals are inhibitory to division; some of them selectively .…”

Genetic Block in the Cellular Division Mechanism of a Morphological Mutant of a Yeast

“…Since the work of Voegtlin and Chalkley (1930), Hammett (1929), Rapkine (1937) and others, there have been many studies in which a specific role for sulfhydryl groups has been implicated in the cellular division process (see reviews by Nickerson, 1948, Scherr andWeaver, 1953). There can be little doubt but that the different investigators have studied more than one reaction since sulfhydryl substances are involved in a multiplicity of cellular reactions.…”

Role of Nutrition in the Maintenance of the Yeast-shape in Candida

“…Effect of cysteine addition to polysaccharide medium.-The necessity for maintenance of intracellular ·SH groupings for increase in cell number has been shown by Hammett (1929) for metazoa, by Voegtlin and Chalkley (1930) for protozoa, and by Nickerson and vanRij (1949) for yeasts. Two enzymatic mechanisms of disulfide reduction have recently been elucidated.…”