The Characteristics of Demineralized Dentin Material Sponge as Guided Bone Regeneration Based on the FTIR and SEM-EDX Tests

Mulyawan, Indra; Danudiningrat, Coen Pramono; Soesilawati, Pratiwi; Aulanni’am, Aulanni’am; Yuliati, Anita; Suroto, Heri; Bramantoro, Taufan; Rizqiawan, Andra; Moon, Seong‐Yong

doi:10.1055/s-0042-1743147

Cited by 9 publications

(10 citation statements)

References 19 publications

(28 reference statements)

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“…However, to date, no animal or human studies have been performed which compare the demineralizing agents used for its production. In vitro elemental analysis of bovine DDM compared with bovine bone-derived matrix revealed that the DDM contains chlorine and calcium in higher concentrations, and this may explain the difference in the osteoconductivity reported between the materials ( Mulyawan et al, 2022 ). Furthermore, it has been proposed that due to the difference between the molecular composition and development of dentin and bone, the extracellular matrices and connective tissue derived from both of these tissues would not only be different but would exert different effects at the implantation site (J. Kim et al, 2021).…”

Section: Resultsmentioning

confidence: 99%

Demineralized dentin matrix for bone regeneration in dentistry: A critical update

Khurshid,

Adanir,

Ratnayake

et al. 2024

The Saudi Dental Journal

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Section: Resultsmentioning

confidence: 99%

Demineralized dentin matrix for bone regeneration in dentistry: A critical update

Khurshid,

Adanir,

Ratnayake

et al. 2024

The Saudi Dental Journal

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“…Furthermore, autologous demineralized dentin represents a source of autogenous growth factors for bone regeneration. 42 Nowadays, the autogenous tooth could be considered as a novel and innovative graft material. 43 The strong points in favor of using such material are it is totally autogenous, it does not require an additional surgical site for harvesting bone graft, the dentin structure and composition are very similar to that of bone, it has been shown to contain BMP-2, that is made available by the demineralization procedure, giving to the material with interesting properties.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Different Techniques in Post-Extractive Socket Regeneration Using Autologous Tooth Graft: Histological and Clinical Outcomes

Minetti,

Palermo,

Berardini

2023

Eur J Dent

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Objective Post-extractive socket grafting techniques reduce alveolar ridge dimensional changes. Numerous graft materials have been suggested and a growing interest in tooth material has been observed as a valuable alternative to synthetic biomaterials or xenografts. Furthermore, different clinical procedures have been proposed for the wound closure of the post-extractive site. This study aims to compare histological and clinical outcomes of two different surgical techniques to seal the post-extractive site with the use of autologous demineralized extracted tooth as graft material. Materials and Methods Sixteen post-extractive socket without buccal and/or palatal bone walls, in sixteen healthy patients, were grafted with the autologous tooth material treated by the new Tooth Transformer device (Tooth Transformer, Milan, Italy). Alveolar socket preservation procedures were performed without flap elevation. Patients were randomly subdivided into two equal groups according to the site closure technique. In group A, the pedunculate tissue was used, while in group B ice cone technique. A bone samples were collected in each site after 4 months for histological analysis. Results No significant clinical differences among the different sealing techniques were observed. In both groups, the site was filled by new bone formation after 4 months of healing. The histological analysis revealed 46.1 ± 8.07% of bone volume, 9.2 ± 9.46% of residual graft, and 35.2 ± 12.36% of vital bone in group A, while group B shows 41.22 ± 5.88% of bone volume, 7.94 ± 7.54% of residual graft, and 31.7 ± 7.52% new bone. No statistical differences were detected (p > 0.05). Conclusion Further studies with a large number of patients, and different observation periods will be needed to confirm the results of this pilot study; however, the interesting data obtained have shown how these techniques, mixed with the autologous dentin derived graft material, seem to promote bone regeneration and reduce physiological bone resorption during alveolar socket preservation treatments.

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“…The carbon that was found in the EDX test is considered organic component. 21 The ability of the membrane to absorb water is presented in ►Fig. 5.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Gamma-Ray Irradiation on the Physical, Mechanical, and Morphological Characteristics of PVA-Collagen-Chitosan as a Guided Tissue Regeneration (GTR) Membrane Material

et al. 2022

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Objective The aim of this study was to evaluate the effect of gamma-ray irradiation on the physical, mechanical, and morphological characteristics of the polyvinyl alcohol (PVA)-collagen-chitosan membranes as a guided tissue regeneration membrane material. Material and Method The membrane was fabricated by mixing PVA, collagen, and chitosan using the film casting method. PVA-collagen-chitosan membranes were irradiated with various radiation dose (0, 15, and 25 kGy). Furthermore, it is characterized using Fourier-transform infrared (FTIR) for functional group identification, morphological test was performed using scanning electron microscopy (SEM), and mechanical properties (i.e., tensile strength and elongation) were evaluated using universal testing machine and swelling studies. Statistical Analysis Statistical analysis was performed based on analysis of variance and post hoc with p-value < 0.05. Result The FTIR spectrum shows various peaks of functional groups from the PVA-collagen-chitosan membrane. The result of the statistical analysis show changes in tensile strength (p = 0.0004) and membrane elongation (p = 0.000451) at different radiation doses of 0, 15, and 25 kGy. The membrane absorption obtains p-value of 0.0193, while the SEM results show that the PVA-collagen-chitosan membrane homogeneously mixed. Conclusion There is an effect of gamma-ray irradiation on tensile strength, elongation, and water absorption of the membranes. Increasing the radiation dose increases the value of tensile strength, while elongation and absorption of the membrane decrease. The PVA-collagen-chitosan membrane has the potential to develop as an alternative membrane for guided tissue regeneration.

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The Characteristics of Demineralized Dentin Material Sponge as Guided Bone Regeneration Based on the FTIR and SEM-EDX Tests

Cited by 9 publications

References 19 publications

Demineralized dentin matrix for bone regeneration in dentistry: A critical update

Demineralized dentin matrix for bone regeneration in dentistry: A critical update

Comparison of Different Techniques in Post-Extractive Socket Regeneration Using Autologous Tooth Graft: Histological and Clinical Outcomes

The Effect of Gamma-Ray Irradiation on the Physical, Mechanical, and Morphological Characteristics of PVA-Collagen-Chitosan as a Guided Tissue Regeneration (GTR) Membrane Material

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