The Change of Prostate Cancer Treatment in Korea: 5 Year Analysis of a Single Institution

Abstract

PurposeWe analyzed changes to the trends of prostate cancer management and patient characteristics at a single institute during 5 years due to the significant increase of the prostate cancer incidence and the robotic equipment in Korea.Materials and MethodsProstate cancer patient data from a single institute recorded from 2006 to 2010 were analyzed. Cancer stage, initial treatment modalities, and the pattern of outpatient clinical management were reviewed.ResultsBetween 2006 and 2010, 386 prostate cancers were newly diagnosed at the institute. The proportion of localized and locally advanced cancer cases increased from 67% in 2006 to 79% in 2010 respectively. Among the treatment choices during follow-up in the out-patients clinic, the proportion of radical prostatectomies increased from 43% in 2006 to 62% in 2010. In contrast, the proportion of hormone therapies decreased from 58% to 37%. For initial treatment choice, radical prostatectomy was chosen for 59% of the patients who were newly diagnosed with cancer during the study period. However, hormone therapy alone was administrated as a primary therapy to 26%. Analysis of the radical prostatectomy subgroup showed that a robot-assisted technique was used in 83% of the patients, and the remaining 17% underwent an open radical prostatectomy.ConclusionAs the prostate cancer incidence increased in Korea, the proportion of localized and locally advanced cancer also increased. In addition, the main treatment modality changed from non-surgical treatment to radical prostatectomy.

Trends in the use of radiation therapy for stage IIA prostate cancer from 2004 to 2013: a retrospective analysis using the National Cancer Database

“…Several recent studies have noted increasing use of RP. 15,16 A Korean study found that the rates of RP for all patients diagnosed with prostate cancer increased from 43% in 2006 to 62% in 2010. 15 This increase in use of prostatectomy, coupled with the associated decrease in radiation use, may largely be due to new surgical techniques and improved side effect profiles.…”

“…15,16 A Korean study found that the rates of RP for all patients diagnosed with prostate cancer increased from 43% in 2006 to 62% in 2010. 15 This increase in use of prostatectomy, coupled with the associated decrease in radiation use, may largely be due to new surgical techniques and improved side effect profiles. For instance, minimally invasive RP with laparoscopy has been shown to decrease the need for blood transfusions, postoperative bleeding, reoperations and length of stay, as compared with more traditional operations.…”

Is High-Dose Leuprorelin Acetate Effective and Safe in Asian Men with Prostate Cancer? An Open-Label, Non-Comparative, Multi-Center Clinical Trial

“…With widespread prostate-specific antigen (PSA) screening, localized prostate cancer has exhibited the greatest increases in incidence rate among prostate cancer cases 2. PSA screening has facilitated discovery of a higher incidence of prostate cancer, as well as stage migration 3.…”

Can Western Based Online Prostate Cancer Risk Calculators Be Used to Predict Prostate Cancer after Prostate Biopsy for the Korean Population?

“…Prostate cancer incidence is very high in the United States and Europe, where prostate-specific antigen (PSA) screening is most common. Recently, there has been a rapid increase of the incidence of prostate cancer in Korean due to an increase in PSA screenings even though the incidence in Asia is lower than in Western countries 1,2. The European Randomized Screening of Prostate Cancer (ERSPC)3-5 and the Prostate Cancer Prevention Trial (PCPT)6,7 have each introduced online prostate cancer risk calculators (RC).…”