The challenge of post-operative peritonitis after gastrointestinal surgery

Sartelli, Massimo; Griffiths, Ewen A.; M, Nestori

doi:10.1007/s13304-015-0324-1

Cited by 21 publications

(12 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Since the reported incidence of both post-operative peritonitis and fistula development are low, no separate analysis was done per birth defect. Post-operative peritonitis in adults is mostly seen as a result of anastomotic leakage, but could also be the result of a bacterial leak from any abdominal organ or the bloodstream [171] . In our infantile cohort we found that post-operative peritonitis and anastomotic leakage both had an incidence of 3%.…”

Section: Discussionmentioning

confidence: 99%

The incidence of abdominal surgical site infections after abdominal birth defects surgery in infants: A systematic review with meta-analysis

Schattenkerk

Musters

Nijssen

et al. 2021

Journal of Pediatric Surgery

View full text Add to dashboard Cite

Background: : Surgical site infections (SSI) are a frequent and significant problem understudied in infants operated for abdominal birth defects. Different forms of SSIs exist, namely wound infection, wound dehiscence, anastomotic leakage, post-operative peritonitis and fistula development. These complications can extend hospital stay, surge medical costs and increase mortality. If the incidence was known, it would provide context for clinical decision making and aid future research. Therefore, this review aims to aggregate the available literature on the incidence of different SSIs forms in infants who needed surgery for abdominal birth defects. Method: : The electronic databases Pubmed, EMBASE, and Cochrane library were searched in February 2020. Studies describing infectious complications in infants (under three years of age) were considered eligible. Primary outcome was the incidence of SSIs in infants. SSIs were categorized in wound infection, wound dehiscence, anastomotic leakage, postoperative peritonitis, and fistula development. Secondary outcome was the incidence of different forms of SSIs depending on the type of birth defect. Meta-analysis was performed pooling reported incidences in total and per birth defect separately. Results: : 154 studies, representing 11,786 patients were included. The overall pooled percentage of wound infections after abdominal birth defect surgery was 6% (95%-

show abstract

Section: Discussionmentioning

confidence: 99%

The incidence of abdominal surgical site infections after abdominal birth defects surgery in infants: A systematic review with meta-analysis

Schattenkerk

Musters

Nijssen

et al. 2021

Journal of Pediatric Surgery

View full text Add to dashboard Cite

show abstract

“…Adhesion formation is started as local inflammatory reaction with fibrinous exudate and fibrin formation [3,4]. Fibrin deposition and degradation balance are important for determining normal peritoneal healing or formation of adhesion [5].…”

Section: Introductionmentioning

confidence: 99%

Anti-adhesive effects of argan oil on postoperative peritoneal adhesions

Aydın¹,

Karakaş²,

Hazer³

et al. 2018

Med-Science

View full text Add to dashboard Cite

The aim of this study is to reveal effect of Argan oil on postoperative peritoneal adhesion. Twenty-four Wistar albino rats were divided into three groups. After laparotomy was carried out intraperitoneally, 0,9% NaCl and 3 ml Argan Oil applied to saline and Argan oil groups, respectively. Four subjects in each groups were sacrificed at postoperative day 3 and 7. Macroscopic adhesions and microscopic cellular reactions, such as giant cell, lymphocyte/plasmocyte, neutrophil and histiocyte, were assessed and hydroxyproline levels were measured in all three groups. Adhesion and fibrosis scores were lower both 3rd and 7th days in Argan oil, but only lower fibrosis scores were statistically significant (p<0,05). Except giant cell 3th day scores; Argan oil had lowest neutrophil, lymphocyte, plasmocyte, and histiyocyte scores. Both 3rd and 7th days scores of neutrophil, lymphocyte, plasmocyte, but only 7th days scores of histiocyte reaction were statistically significant (p<0,05). However; Argan oil had highest hydroxyproline levels and the difference were not statistically significant both 3rd and 7th days (p>0,05). Argan oil reduced the postoperative peritoneal adhesions initially seperation the damaged tissues, subsequent effects of fatty acids and tocopherols on inflammation, plasminogen activation and matrix metalloproteinase steps of adhesion formation.

show abstract

“…Nevertheless, none of them is fully accepted, due to several reasons, including a large number of parameters that determine the complexity of use, low informative methods based on a small number of criteria, etc. As a result, APACHE, SAPS, SOFA and other scales [8][9][10][11][12][13][14][15][16] which allow estimating the severity of the patients and the possibility of death are suggested for predicting the effects of treatment. Mannheim peritonitis index (MPI) [5] is acknowledged in many countries, but its only function is determination of the peritonitis severity.…”

Section: Introductionmentioning

confidence: 99%

Management of postoperative complications in patients with acute peritonitis

2020

Biointerface Res Appl Chem

View full text Add to dashboard Cite

Acute peritonitis remains one of the most severe and threatening abdominal cavity disease. An important component of the treatment of acute peritonitis is the ability to prognosis adequately the possibility of postoperative complications, which allows using appropriate preventive measures. For the case, numerous methods, based on the account of various parameters, are developed. Nevertheless, none of them is fully accepted, and useful. The purpose was to develop an informative scale for postoperative complications predicting. The retrospective analysis of the outcome of treatment of 169 patients with acute surgical pathology of abdominal organs complicated by various forms of peritonitis, 79 of whom developed postoperative complications results are presented. The dependence of occurrence and severity of complications on the nature of the underlying disease, clinical manifestations of peritonitis before surgery, anthropometric data research, laboratory methods, Mannheim peritonitis index parameters, comorbidity class, and age were studied, using the analysis of variance. A scale, according to which the prediction of complications is conducted in two stages, was developed. Before the surgery, we estimate the previous risk according to the nature of the underlying disease, clinical manifestations of peritonitis, comorbidity class. According to identified changes, the final estimation due to the nature of the underlying disease, Mannheim peritonitis index parameters, comorbidity class, stab neutrophil leukocytes number, use of programmed peritoneal cavity sanations is being made during the operation. These indicators provided a certain number of points. Due to these points, patients were referred to several groups: normal group (less than 18), increased (18-25), and medium (26-34) and high (more than 35) the risk of complications. The developed scale makes it possible to apply the necessary preventive measures at all stages of treatment, since preoperative preparation.

show abstract

The challenge of post-operative peritonitis after gastrointestinal surgery

Cited by 21 publications

References 72 publications

The incidence of abdominal surgical site infections after abdominal birth defects surgery in infants: A systematic review with meta-analysis

The incidence of abdominal surgical site infections after abdominal birth defects surgery in infants: A systematic review with meta-analysis

Anti-adhesive effects of argan oil on postoperative peritoneal adhesions

Management of postoperative complications in patients with acute peritonitis

Contact Info

Product

Resources

About