The cerebellum: Its role in language and related cognitive and affective functions

Smet, Hyo Jung De; Paquier, Philippe; Verhoeven, Jo; Mariën, Peter

doi:10.1016/j.bandl.2012.11.001

Cited by 215 publications

(152 citation statements)

References 98 publications

Supporting

Mentioning

138

Contrasting

Unclassified

Order By: Relevance

“…Since then cerebellar involvement in linguistic processes has been studied by advanced neuroimaging methods in healthy subjects and a number of studies have been published focusing on a variety of linguistic dysfunctions following cerebellar lesions of different etiologies in children as well as adults. Reviews of the role of the cerebellum in nonmotor language functions are provided by Gordon [26], Mariën et al [27], Paquier and Mariën [28], De Smet et al [29, 30], Beaton and Mariën [31], Murdoch [32], and Highnam and Bleile [33]. …”

Section: Introductionmentioning

confidence: 99%

Consensus Paper: Language and the Cerebellum: an Ongoing Enigma

Mariën

Ackermann

Adamaszek³

et al. 2013

Cerebellum

Self Cite

319

351

View full text Add to dashboard Cite

In less than three decades, the concept “cerebellar neurocognition” has evolved from a mere afterthought to an entirely new and multifaceted area of neuroscientific research. A close interplay between three main strands of contemporary neuroscience induced a substantial modification of the traditional view of the cerebellum as a mere coordinator of autonomic and somatic motor functions. Indeed, the wealth of current evidence derived from detailed neuroanatomical investigations, functional neuroimaging studies with healthy subjects and patients and in-depth neuropsychological assessment of patients with cerebellar disorders shows that the cerebellum has a cardinal role to play in affective regulation, cognitive processing, and linguistic function. Although considerable progress has been made in models of cerebellar function, controversy remains regarding the exact role of the “linguistic cerebellum” in a broad variety of nonmotor language processes. This consensus paper brings together a range of different viewpoints and opinions regarding the contribution of the cerebellum to language function. Recent developments and insights in the nonmotor modulatory role of the cerebellum in language and some related disorders will be discussed. The role of the cerebellum in speech and language perception, in motor speech planning including apraxia of speech, in verbal working memory, in phonological and semantic verbal fluency, in syntax processing, in the dynamics of language production, in reading and in writing will be addressed. In addition, the functional topography of the linguistic cerebellum and the contribution of the deep nuclei to linguistic function will be briefly discussed. As such, a framework for debate and discussion will be offered in this consensus paper.

show abstract

Section: Introductionmentioning

confidence: 99%

Consensus Paper: Language and the Cerebellum: an Ongoing Enigma

Mariën

Ackermann

Adamaszek³

et al. 2013

Cerebellum

Self Cite

319

351

View full text Add to dashboard Cite

show abstract

“…The feedback or efferent loop originates from the deep nuclei of the cerebellum, which project to the nuclei of the thalamus. In turn, the nuclei of the thalamus project to the motor and premotor cortices and also to nonmotor areas including the prefrontal cortex (Marien, Engelborghs, Fabbro, & De Deyn, 2001;Smet, Paquier, Verhoeven, & Mariën, 2013). Several clinical reports suggest evidences for cerebello-thalamo-cortical pathways.…”

Section: Discussionmentioning

confidence: 98%

Memory impairment following right cerebellar infarction: a case study

et al. 2014

View full text Add to dashboard Cite

We reported a patient with a right cerebellar infarction who showed anterograde amnesia. Cognitive dysfunction caused by cerebellar lesions was called cerebellar cognitive affective syndrome, and deactivation of the contralateral prefrontal cortex function due to disconnections of cerebello-cerebral fiber tracts have been hypothesized as mechanism underlying the syndrome. The episodic memory impairment, however, could not be supported by the same mechanism because the prefrontal lesions cannot cause amnesia syndrome. The feature of the impairment of our patient was similar to that of diencephalic amnesia, and a single photon emission computed tomography study showed a relative hypoperfusion in the right cerebellar hemisphere and left anterior thalamus. We considered that the memory deficit was caused by the dysfunction of the thalamus, which is a relay center of the cerebello-cerebral connectivity network.

show abstract

“…4 El córtex frontal y los ganglios basales, implicados en la cognición y en el procesamiento afectivo, podrían inhibirse debido a una lesión cerebelosa que induciría cambios en la concentración de neurotransmisores desde el cerebelo hasta regiones supratentoriales a través de la vía cerebelo-ponto-tálamo-cortical. 5 Varios estudios encuentran atrofia cerebelosa y menor activación del lóbulo prefrontal en pruebas de imagen funcional de pacientes con TDAH respecto a los controles, es decir, relacionan una lesión cerebelosa con sintomatología propia del córtex prefrontal (cambios en la conducta, impulsividad, inatención).…”

Section: Discussionunclassified

“…7,8 Las lesiones cerebelosas se asocian e270 / Arch Argent Pediatr 2015;113(5):e268-e270 / Presentación de casos clínicos a déficits verbales, tales como dificultades en la formulación de una semántica y sintaxis correcta, en la articulación y fluidez del discurso, en la lectura y en la escritura. 4 Algunos autores relacionan estas deficiencias verbales con el hemisferio cerebeloso derecho 7 y otros no encuentran evidencia para afirmar que existe lateralización. 9 Tampoco encuentran relación con el tipo de lesión cerebelosa (atrófica o focal).…”

Section: Discussionunclassified

Síndrome cerebeloso cognitivo-afectivo

Garriga-Grimau

Laín

Nascimiento³

et al. 2015

Arch Argent Pediat

View full text Add to dashboard Cite

Presentación de casos clínicos RESUMENIntroducción. El diagnóstico de síndrome cerebeloso cognitivo afectivo se debe realizar en aquellos pacientes con lesiones cerebelosas y con déficit cognitivo asociado a deficiencias neuropsicológicas visoespaciales o ejecutivas, trastornos del lenguaje expresivo y trastornos afectivos. Caso clínico. Adolescente de 16 años diagnosticada con trastorno por déficit de atención e hiperactividad a los 7 años, que presenta inestabilidad emocional, apatía y discurso y lectura poco fluidos. Se observan deficiencias visoespaciales en los tests neuropsicológicos. Se realiza una resonancia magnética cerebral por presentar alteración de la coordinación y motricidad fina, y se evidencia atrofia de vermis cerebeloso. La sintomatología es compatible con síndrome cerebeloso cognitivo afectivo. Clásicamente, el cerebelo es conocido por su rol motor. Sin embargo, está implicado en funciones cognitivas superiores, en la expresión emocional y en la regulación conductual. El síndrome cerebeloso cognitivo afectivo es una entidad no bien conocida que debemos incluir en el diagnóstico diferencial de trastornos neuropsiquiátricos con lesión cerebelar. Palabras clave: cerebelo, trastornos cognitivos, trastornos afectivos, trastorno por déficit de atención con hiperactividad, síndrome cerebeloso cognitivo-afectivo.

show abstract

The cerebellum: Its role in language and related cognitive and affective functions

Cited by 215 publications

References 98 publications

Consensus Paper: Language and the Cerebellum: an Ongoing Enigma

Consensus Paper: Language and the Cerebellum: an Ongoing Enigma

Memory impairment following right cerebellar infarction: a case study

Síndrome cerebeloso cognitivo-afectivo

Contact Info

Product

Resources

About