From the Editors I t will take years before we can understand and measure the full toll that the COVID-19 pandemic has taken on our health systems. Of the many reverberations from the pandemic, one of the most concerning implications is an increase in the rates of preventable harm. Four years of unprecedented demand on healthcare services combined with health human resource shortages and clinician burnout have pushed our systems to the brink -and are impacting our capacity to improve or even maintain standards of care.This edition of Healthcare Quarterly highlights concerns related to patient safety and harm and introduces a focus on organizations that are defying the odds. This year, we intend to draw greater attention to this topic and include examples of organizations that have built resiliency into patient safety systems and/or are taking steps to get back on track with improvement goals. We are pleased to be able to share insights from Ross Baker, one of Canada's pre-eminent experts on the topic of patient safety, who is contributing thought leadership to the current state of patient safety and discusses why we need to be paying attention (Baker 2024). Baker's (2024) special commentary provides additional insight into the article by Harvey et al. ( 2024) on building a resilient patient safety culture in a large multi-site hospital, as well as a recent analysis from the Canadian Institute for Health Information (CIHI) that explores the correlation between hospital staffing issues and patient harm during the pandemic. This commentary replaces our regular featured column on Quality 2.0 from Leslee Thompson. Thompson's column will return in our next edition (see Thompson 2023Thompson , 2024.In addition to our focus on patient safety and harm, the articles include a primer on artificial intelligence (AI) for leaders, as well as an overview of emerging leadership models. We also highlight a case study on the benefits of engaging patients in improving transitions from hospital, complemented by an invited essay on the future of co-design with patients and caregivers from the perspectives of three researchers working with Ontario Health Teams (OHTs). We conclude with our regular featured columns from our colleague Neil Seeman as well as those from ICES and CIHI (Campbell et al. 2024;Seeman 2024;St. Cyr and Mahar 2024).We would like to thank the authors who have contributed abstracts on mental health and substance use disorder related to our recent call for papers on this topic. We are working with Ruby Brown, our special guest co-editor, to start publishing examples of teams from across Canada that are doing exemplary work in this important area. Stay tuned as we work with the authors to finalize these articles for publishing in upcoming editions.