The burden of osteoarthritis: development and validation of a new assessment tool (BONe’S)

Rannou, François; Bertin, Philippe; Grange, Laurent; Branchoux, S.; Dachicourt, J.-N.; Taïeb, C.

doi:10.1185/03007995.2013.876978

Cited by 6 publications

(6 citation statements)

References 36 publications

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“…Besides, different health authorities (NICE in UK, HMO in the USA, HAS in France) take into account the individual burden of the disease in order to prioritize and determine the level of reimbursement of medical products. Individual burden accounts for the broadest aspects of disease-related disability, including psychological, physical, social, and economic factors (Dufresne et al, 2013;Leidy et al, 1999;Rannou et al, 2014;Seidenberg et al, 1994;Taieb et al, 2014) and may help to monitor specific disease before and after therapy.…”

Section: Discussionmentioning

confidence: 99%

The Vitiligo Impact Patient Scale (VIPs): Development and Validation of a Vitiligo Burden Assessment Tool

Salzes

Abadie²,

Sénéschal³

et al. 2016

Journal of Investigative Dermatology

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101

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Vitiligo has a major impact on health-related quality of life (QOL). Although a few vitiligo specific QOL instruments exist, there is no specific vitiligo burden tool. We developed and validated a specific vitiligo burden tool according to skin phototype. In total, 301patients completed 35-item of the Vitiligo Impact Patient scale (VIPs) of who 235 were of skin phototype I to III and 66 of phototype IV to VI. The dimensionality of the items was evaluated using factor analyses with results suggesting 3 factors in fair and dark skinned patients ("Psychological effects on daily life", "Relationships and Sexuality", and "Economic constraints, Care & Management of Disease"). Unidimensionality was confirmed by higher order factor analysis. Cronbach's α were high and intra-dimensional coherences all demonstrated good reliability (α>0.8). The final instrument consists of 29 items (19 items common to all patients, 3 specific to fair skin and 7 to dark skin. The test-retest reliability demonstrated very good reproducibility. Intra Class Correlation of each dimension was >0.90 for each population. External validity was confirmed by the correlation coefficients and Bland and Altman plots of the VIPs-FS and VIPs-DS versus the SF-12, PVC Metra, BISS and DLQI assessment tools.Journal of Investigative Dermatology accepted article preview online, 08 October 2015. doi:10.1038/jid.2015.398.

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Section: Discussionmentioning

confidence: 99%

The Vitiligo Impact Patient Scale (VIPs): Development and Validation of a Vitiligo Burden Assessment Tool

Salzes

Abadie²,

Sénéschal³

et al. 2016

Journal of Investigative Dermatology

Self Cite

101

View full text Add to dashboard Cite

show abstract

“…The notion of individual burden accounts for the broadest aspects of disease-related disability, covering psychological, physical, social, and economic factors, simultaneously taking into account QoL, community integration, organization of everyday life, and medical resource consumption. This overarching burden can be evaluated directly and specifically among patients with a particular disease (18)(19)(20)(21)(22).…”

Section: Discussionmentioning

confidence: 99%

“…The notion of burden has recently been extended to individuals and their families, to assess disability (e.g. health-related QoL (HRQoL), social integration, homelife, and use of medical resources (including consultations/medications)) in the broadest sense of the term (psychological, social, economic and physical), related to various diseases including chronic venous disorders (18), hand-foot syndrome (19), infantile haemangioma (20), inherited ichthyosis (21), and osteoarthritis (22).…”

mentioning

confidence: 99%

Atopic Dermatitis Burden Scale for Adults: Development and Validation of a New Assessment Tool

Taı̈eb¹,

Boralévi²,

Sénéschal³

et al. 2015

Acta Derm Venerol

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Atopic dermatitis (AD) occurs in approximately 2-3% of adults. The aim of this study was to develop and validate the self-administered Atopic Dermatitis Burden Scale for Adults (ABS-A). Patients were enrolled consecutively from those attending the Station Thermale Avène for a diagnosis of AD. ABS-A was developed using standard methodology, and consisted of 3 phases: exploratory, development, and validation. Internal consistency (Cronbach's α), concurrent validity (Spearman's correlation between ABS-A, SF-12 and Dermatology Life Quality Index [DLQI)]), and discriminant validity, were analysed. A total of 128 adults (68.8% females) completed the ABS-A, consisting of 18 items grouped into 4 domains. ABS-A showed good internal coherence (Cronbach's α, 0.89) and was correlated with both SF-12 components [r = -0.36, p < 0.0001 (Physical); r = -0.52, p < 0.0001 (Mental)] and DLQI (r = 0.78; p < 0.0001). The ABS-A score varied significantly according to AD severity. To our knowledge, ABS-A is the first specific tool for assessing AD burden in adult patients.

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“…It is also predicted to be the single greatest cause of disability in the general population by 2030 (1), with an estimated 35% of people eventually suffering from OA. Disease rate is likely to increase year by year continuously as the global population ages and working lives become longer in developed countries (2). Despite its high prevalence and substantial public health impact, disease etiology remains incompletely understood.…”

Section: Introductionmentioning

confidence: 99%

Recent advances in the understanding of molecular mechanisms of cartilage degeneration, synovitis and subchondral bone changes in osteoarthritis

Wei

Bai

2016

Connective Tissue Research

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Osteoarthritis (OA), the most common form of degenerative joint disease, is linked to high morbidity. It is predicted to be the single greatest cause of disability in the general population by 2030. The development of disease-modifying therapy for OA currently face great obstacle mainly because the onset and development of the disease involve complex molecular mechanisms. In this review, we will comprehensively summarize biological and pathological mechanisms of three key aspects: degeneration of articular cartilage, synovial immunopathogenesis, and changes in subchondral bone. For each tissue, we will focus on the molecular receptors, cytokines, peptidases, related cell, and signal pathways. Agents that specifically block mechanisms involved in synovial inflammation, degeneration of articular cartilage, and subchondral bone remodeling can potentially be exploited to produce targeted therapy for OA. Such new comprehensive agents will benefit affected patients and bring exciting new hope for the treatment of OA.

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The burden of osteoarthritis: development and validation of a new assessment tool (BONe’S)

Abstract: The BONe'S questionnaire is a short (20-item) validated tool for evaluating the specific individual burden of OA in a holistic manner.

Cited by 6 publications

References 36 publications

The Vitiligo Impact Patient Scale (VIPs): Development and Validation of a Vitiligo Burden Assessment Tool

The Vitiligo Impact Patient Scale (VIPs): Development and Validation of a Vitiligo Burden Assessment Tool

Atopic Dermatitis Burden Scale for Adults: Development and Validation of a New Assessment Tool

Recent advances in the understanding of molecular mechanisms of cartilage degeneration, synovitis and subchondral bone changes in osteoarthritis

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