The burden of gastroesophageal reflux disease on patients’ daily lives: A cross-sectional study conducted in a primary care setting in Serbia

Bjelović, Miloš; Babic, Tamara; Dragicevic, Igor; Ćorac, Aleksandar; Trajković, Goran

doi:10.2298/sarh1512676b

Cited by 4 publications

(3 citation statements)

References 24 publications

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“…Patients with FD experienced more days with poor sleep compared to the GERD group. Sleep disorders are quite common medical problems, and have been associated with several diseases, including GERD and FD [10].…”

Section: Discussionmentioning

confidence: 99%

“…Recently published studies have addressed the significant impairment of health-related quality of life (HRQoL) in patients suffering from GERD in the areas of eating and drinking, physical activity, psychological wellbeing, as well as reduced vitality and poor sleep [6][7][8][9][10]. Furthermore, studies have shown that the direct costs of GERD range between PPP$172 (purchasing power parity in US dollars) and PPP$176 per person per year, thus causing a substantial economic burden [11,12].…”

Section: Introductionmentioning

confidence: 99%

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Gastroesophageal reflux disease and functional dyspepsia: What is the real burden on health-related quality of life?

Babic¹,

Dragicevic

Ćorac

et al. 2018

Srp Arh Celok Lek

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Introduction/Objective Recently published studies have addressed the significant impairment of healthrelated quality of life (HRQoL) in patients suffering from gastroesophageal reflux disease (GERD) and functional dyspepsia (FD). To the best of our knowledge, none of the previously published studies have compared the impact of GERD and FD on HRQoL. The aim of the study was to determine the impact of GERD and FD on HRQoL. Methods The current sample was extrapolated from a large cross-sectional population-based study conducted in primary health care facilities. Primary care physicians and general internists diagnosed GERD according to the Montreal definition for population-based studies. Also, primary care physicians and general internists diagnosed FD based on the Rome III criteria. The Serbian version of the generic self-administered Center for Disease Control and Prevention questionnaire was used. We used the propensity score method to match GERD and FD samples on variables such as age, gender, education, and adherence to therapy. Results Regarding self-rated health, similar results were obtained from both groups. The Center for Disease Control and Prevention HRQoL questionnaire version 4 further revealed that functional dyspepsia led to greater disturbances of everyday functioning in regard to the criteria of physically healthy, mentally healthy, and activity limitation days. Conclusion The results of the study have shown significant impairment of HRQoL in both groups, but, surprisingly, patients with FD experienced more limitations to their everyday functioning compared to patients with GERD.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Gastroesophageal reflux disease and functional dyspepsia: What is the real burden on health-related quality of life?

Babic¹,

Dragicevic

Ćorac

et al. 2018

Srp Arh Celok Lek

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“…In this study, we utilized the overall health condition by the Serbian version of the self-administered questionnaire CDC-HRQoL-4. We have already used this questionnaire for the evaluation of patients with gastroesophageal reflux disease (GERD) 11 .…”

Section: Discussionmentioning

confidence: 99%

Health-related quality of life in patients with functional dyspepsia

Bjelović¹,

Zaric²,

Babic³

et al. 2017

VOJNOSANIT PREGL

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Background/Aim. Recent population based studies have proved that patients with functional dyspepsia (FD) have a significantly impaired health-related quality of life HRQoL as compared to general population. The aim of the study was to evaluate the impact of FD on (HRQoL) in patients treated in primary healthcare settings in Serbia. Methods. The study involved 1,448 patients with FD. The diagnosis was made by a general practice physician or gastroenterologist using the Rome III diagnostic criteria. The Serbian version of the questionnaire for the assessment of HRQoL of the U.S. Department of Health and Human Services' Centers for Disease Control and Prevention (HRQoL-4 item CDC) was used for data collection, while descriptive statistical measurements were applied to calculate standard deviation, frequency as well as multiple logistic regression model. Results. Out of the total number of patients, 41.8% assessed their health condition as seriously disordered or poor. The mean values of health disorder duration over the last 30 days was 11.8 days, disordered physical health 7.2 days, mental disorder 6.3 days, and activity limitation 5.1 days. Also, 29.7%, 15.2%, 12.8% and 10.7% of the patients reported ≥ 14 unhealthy days, ≥ 14 physically unhealthy days, ≥ 14 mentally unhealthy days and ≥ 14 activity limitation days, respectively. Conclusion. From patients' perspective, FD has a significant impact on HRQoL. In this study, 41.8% of the patients described their health status as fair or poor, and FD significantly affects all aspects of life, both mental and physical. The recognition of that impact is probably the most important step towards appropriate treatment and decreasing HRQoL impairment in patients with FD.

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Quality of life in patients with diabetes - limited activity hinders women more

Polovina,

Terzic-Supic,

Micic

et al. 2023

Srp Arh Celok Lek

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Introduction/Objective. Diabetes mellitus and its chronic complications impair quality of life when compared to the one of the general population. The objective of this study was to determine the prevalence of > 14 unhealthy days per month among the patients with diabetes in Serbia and to determine the association of the socio-demographic characteristics and health characteristics with the total of > 14 unhealthy days. Methods. Serbian version of a generic self-administered questionnaire from Centers for Disease Control and Prevention (CDC-HRQOL-4) was used for data collection in all three levels of care. Results. The study involved 4898 patients with diabetes, 2283 (46.6%) men and 2611 (53.4%) women. Overall mean age was 57.3 ? 12.2 years with over one fifth (23.2 %) were younger than 50 years. Multivariate logistic regression analyses indicated that age > 65 (OR:1.575, 95%CI 1.100-2.256), being a woman (OR: 1.287, 95% CI 1.042-1.588), lower education (OR: 1.383, 95%CI 1.091-1.754), felt depressed ? 14 days (OR: 3.689, 95% CI 2.221-6.128), felt anxious ? 14 days (OR: 1.749, 95% CI 1.113-2.749), poor sleep ? 14 days (OR:2.161, 95%CI 1.569-2.988), fair or poor self-rated health ? 14 days (OR: 4.322, 95%CI 3.474-5.376) were associated with unhealthy days ? 14 days. The strongest negative association was observed between limited physical activity ? 14 days and a decrease in the quality of life of people with diabetes (OR: 22.176, 95%CI 10.971-44.824). Conclusion. This study highlights association between impaired quality of life in patients with diabetes and physical activity limitations. Limited physical activity is the factor with the greatest negative impact on the quality of life particularly in older, less educated women with diabetes.

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The burden of gastroesophageal reflux disease on patients’ daily lives: A cross-sectional study conducted in a primary care setting in Serbia

Abstract: This study addressed complex relationships between reflux symptoms and patients'impaired everyday lives.

Cited by 4 publications

References 24 publications

Gastroesophageal reflux disease and functional dyspepsia: What is the real burden on health-related quality of life?

Gastroesophageal reflux disease and functional dyspepsia: What is the real burden on health-related quality of life?

Health-related quality of life in patients with functional dyspepsia

Quality of life in patients with diabetes - limited activity hinders women more

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