“…Infants with Factor XIII deficiency can present with umbilical stump bleeding and delayed separation of the umbilical cord. About one third of infants with the condition can also present with devastating intracranial hemorrhage, thus mimicking potential abusive head trauma [de Jager et al, 2014]. It is important to note that standard coagulation testing with prothrombin time, activated partial thromboplastin time, and platelet function tests are normal in congenital Factor XIII deficiency; therefore, specific Factor XIII assays must be utilized, and therefore suspected, in order to secure the diagnosis [Gordon et al, 2008].…”