The Budd-Chiari Syndrome: Correlation Between Hepatic Scintigraphy and the Clinical, Radiological, and Pathological Findings in Nineteen Cases of Hepatic Venous Outflow Obstruction

Tavill, Anthony S.; Wood, Eleanor; Kreel, L.; Jones, Elizabeth A. V.; Gregory, M Mundis; Sherlock, Sheila

doi:10.1016/s0016-5085(75)80090-4

Cited by 179 publications

(53 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[4][5][6]9,19,26,28,29 Until recently, scintigraphy and venography, along with liver biopsy, were very important investigations for the diagnosis of HVOO. 10,11,21 However, recently CT, 12 MRI, 13 ultrasonography 14 and pulsed Doppler sonography [15][16][17] have also been shown to be useful. Bolondi et al, in their series of HVOO, showed pulsed Doppler ultrasound to be accurate in 87.5% of cases.…”

Section: Discussionmentioning

confidence: 99%

Budd–Chiari syndrome: Our experience of 71 patients

Singh¹,

Sinha²,

Nain³

et al. 2000

J of Gastro and Hepatol

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Budd–Chiari syndrome: Our experience of 71 patients

Singh¹,

Sinha²,

Nain³

et al. 2000

J of Gastro and Hepatol

View full text Add to dashboard Cite

show abstract

“…Albuminuria may be present as a result of the IVC hypertension. Sparing of an enlarged caudate lobe ('hot spot') on radionuclide scanning, characteristic of hepatic vein thrombosis (38), may not be seen with MOIVC (18), and this is sometimes helpful. Ultrasonography and computed tomography with contrast enhancement may suggest the diagnosis, and oesophago-gastric varices may be seen on gastroscopy or contrast medium examination.…”

Section: Clinical Presentation and Diagnosismentioning

confidence: 99%

“…Radionuclide venography may be a useful screening test (39) but a definitive diagnosis requires contrast inferior vena cavography (6,7,9,13,36,38). Because the thickness of the occlusive lesion is a crucial factor in planning the treatment of MOIVC, inferior vena cavography should be combined with visualization of the upper end of the obstruction by means of a catheter introduced into the right atrium.…”

Section: Clinical Presentation and Diagnosismentioning

confidence: 99%

“…Filling defects caused by thrombi may be present below and above the occlusive lesion. Transhepatic measurement of hepatic venous and portal pressures shows hepatic vein pressure to be equal to or greater than portal pressure, and intra-hepatic injection of contrast medium reveals aberrant hepatic venous drainage (38).…”

Section: Clinical Presentation and Diagnosismentioning

confidence: 99%

See 1 more Smart Citation

Membranous obstruction of the inferior vena cava and its causal relation to hepatocellular carcinoma

Kew

Hodkinson

2005

Liver International

View full text Add to dashboard Cite

Although rare in most countries, membranous obstruction of the inferior vena cava (MOIVC) occurs more frequently in Nepal, South Africa, Japan, India, China, and Korea. The occlusive lesion always occurs at approximately the level of the diaphragm. It commonly takes the form of a membrane, but may be a fibrotic occlusion of variable length. Controversy exists as to whether MOIVC is a developmental abnormality or a result of organization of a thrombus in the hepatic portion of the inferior vena cava. The outstanding physical sign associated with MOIVC are large truncal collateral vessels with a cephalad flow. A dilated vena azygous is seen on chest radiography. Definitive diagnosis is made by contrast inferior vena cavography. The long-standing obstruction to hepatic venous flow causes severe centrolobular fibrosis and predisposes to the development of hepatocellular carcinoma (HCC). Percutaneous balloon angioplasty, transatrial membranotomy, or more complex vena caval and portal decompression surgery should be performed to prevent these complications. HCC occurs in more than 40% of South African Black and Japanese patients with MOIVC, but less often in other populations. It is thought to result from the tumour-promoting effect of continuous hepatocyte necrosis, although the associated environmental risk factors have not been identified.Key words: centrolobular hepatic fibrosishepatic venous hypertension -hepatocellular carcinoma -inferior vena cavography -membranous obstruction of the inferior vena cava

show abstract

“…8,11 Obstruction of hepatic veins often is asynchronous, leading to the coexistence of areas with various degrees of liver injury. 12,13 The anatomic configuration of the major hepatic veins shows variations in approximately 10% to 15% of individuals. 6,[14][15][16][17] When two or more major hepatic veins become occluded, there is an associated increased pressure and reduced flow in the hepatic sinusoids.…”

mentioning

confidence: 99%

Surgical treatment of Budd-Chiari syndrome

Klein¹

2003

Liver Transplantation

View full text Add to dashboard Cite

The Budd-Chiari Syndrome: Correlation Between Hepatic Scintigraphy and the Clinical, Radiological, and Pathological Findings in Nineteen Cases of Hepatic Venous Outflow Obstruction

Cited by 179 publications

References 21 publications

Budd–Chiari syndrome: Our experience of 71 patients

Budd–Chiari syndrome: Our experience of 71 patients

Membranous obstruction of the inferior vena cava and its causal relation to hepatocellular carcinoma

Surgical treatment of Budd-Chiari syndrome

Contact Info

Product

Resources

About