The blood-storing ability of the spleen

Udroiu, Ion

doi:10.15298/rusjtheriol.07.2.07

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…Spleen phylogeny is highly complex. It was proposed from a primitive type with a closed circulation,characteristic of monotremes, insectivores and tree shrews,to archetypal type with open circulation,peculiar to mice, gerbils, bats and marsupials.Further evolved into bloodstoring spleens(ungulates and carnivores) and defensive spleens(old world monkeys and rodents).Xenathra group of placental mammals which are represented by ant eaters, sloths, armadillos show haemopoesis with open circulation.With the appearance of bloodforming bone marrow,splenic erythropoiesis was no longer essential.This resulted in the spleen to become more involved in immunological processes and developed a specialized white pulp.In mammalian spleens the white pulp reached the highest degree of specialization among all vertebrates.Thus spleen further evolved in man to defensive and sinusal type.Defensive type was characterized by the predominance of white pulp in comparison to red pulp [7].…”

Section: Discussionmentioning

confidence: 99%

Morphological Study of Spleen and Variations in South Indian Population

Chelladurai¹,

Jacinth²,

Ramamani³

et al. 2019

IJAR

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Background and Aim:The spleen is the largest lymphoid organ in the human body. It is highly vascular and friable.It is affected in various clinical conditions like infections and storage functions. The aim of the study is to find out the morphological variations of spleen.The present study is undertaken to report the prevalence of variations involving weight, length, breadth, width (thickness) and the number of notches of spleen in the cadavers of South India population. Materials and Methods:The study was done in 50 human adult cadaveric spleens of both sexes preserved in 10% formalin. The weight, length, breadth, thickness were measured and the number of notches present were noted.Results:The weight of fifty spleens studied varied from 80-200gm in 43(86%), 201-300gm in 6 (12%) and above 300gm in 1(2%) , the length of the spleen on the visceral surface measured from upper pole to lower pole varied from 6-9cm in 25(50%) and 10-15 cm in 25 (50%) .The breadth of the spleen varied from 2-5 cm in 16 (32%) specimen, 6-9 cm in 32 (64%) specimen and 10-13 cm in 2 (4%) specimen respectively. The width (thickness) taken at the midpoint of the spleen varied from 2-4 cm in 48 (96%) specimen and 5-6 cm in 2 (48%) specimen respectively.In the present study the number of notches varied from zero to six, but in most of the specimens there were one or two notches.However accessory spleen was not found at the hilum of thespleen. Conclusion:The findings of the present study will be of fundamental importance to the physicians,surgeons and radiologists.It also furnishes much insights on clinical utility and significance of spleen.

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Section: Discussionmentioning

confidence: 99%

Morphological Study of Spleen and Variations in South Indian Population

Chelladurai¹,

Jacinth²,

Ramamani³

et al. 2019

IJAR

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The Phylogeny of the Spleen

Udroiu¹,

Sgura²

2017

The Quarterly Review of Biology

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The spleen can exert different functions: hematopoiesis, immune response, blood filtration, and blood storage. Presence and importance of each function vary among different species and, within a single species, vary during ontogeny. During the course of evolution, loss of hematopoietic functions was accompanied by increased specialization of other functions. Increase in the complexity of immunological features can be seen in the passage from scattered lymphocytes to segregation of the white pulp, organization of T- and B-lymphocyte regions and, finally, appearance of germinal centers. The red pulp remained essentially the same in all nonmammalian vertebrates, with a microarchitecture that concentrates blood and allows its filtration. In our view, this high splenic hematocrit was eventually co-opted in teleosts and mammals to develop a new function: the storage of red blood cells. Finally, mammalian species evolved different features of the red pulp, increasing the specialization of the filtration function (pulp sinuses) and/or storing function (muscularization)

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Gross morphometrical postnatal developmental studies on spleen of Chotanagpuri sheep (Capra ovis)

Mehta¹,

Deshmukh²,

Minj³

et al. 2016

VSRJ

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This study involved morphologic and morphometric postnatal development on thirty spleens of the Chotanagpuri sheep. The spleen was collected and biometrical parameters were recorded. The spleen was found high in the abdominal cavity adjacent to the vertebral column in the region of 10-13 th ribs in all age group. The colour of spleen varied with advancement of age which was creamish in early age and gradually became reddish brown. The shape of the spleen was roughly triangular in all age groups. The mean weight, maximum length, maximum width, length of dorsal, anterior and posterior borders and thickness of dorsal border at anterior, middle and posterior ends, thickness of anterior border at dorsal and middle ends, thickness of posterior border at dorsal end of spleen and distance of hilus from dorsoanterior and ventro-anterior angle significantly increased among different groups of sheep with advancement of age. However, there was no significant difference in thickness of anterior border at ventral end, thickness of posterior border at middle and ventral ends.

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The blood-storing ability of the spleen

Cited by 3 publications

References 18 publications

Morphological Study of Spleen and Variations in South Indian Population

Morphological Study of Spleen and Variations in South Indian Population

The Phylogeny of the Spleen

Gross morphometrical postnatal developmental studies on spleen of Chotanagpuri sheep (Capra ovis)

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