With the rapid development of information technology and computer network technology, the era of artificial intelligence has come. In the era of artificial intelligence, VR technology has been widely used in various fields. As an indispensable part of enterprise management, human resource management has attracted the attention of major enterprises and institutions. There are more and more researches on enterprise human resource management, but human resource management must keep up with the pace of the times, so it needs continuous innovation. Based on the background of artificial intelligence era, combined with the current hot VR technology, this paper analyzes the demand, establishes a VR enterprise human resource management system with more complete functions, and tests the system. After passing the test, it was put into the human resource management of company C. After three months of trial operation, the satisfaction and learning effect of employees were investigated and analyzed, and the cost of human resource management of company C before and after the human resource management system was put into use was compared. The experimental results show that 76% of the employees are very satisfied with the system, and 79 employees think that the training and learning effect of the system is very good. The human resource management cost before and after the system is used has changed significantly, and the human resource cost has been reduced by 39630 yuan. This shows that under the background of artificial intelligence era, the application of VR technology in enterprise human resource management can improve the efficiency of enterprise human resource management, reduce costs, improve employee satisfaction, so as to enhance the competitiveness of enterprises.